Interleukin-10 and chronic liver disease.

Zhang LJ; Wang XZ

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Interleukin-10 and chronic liver disease.

机译：白介素10和慢性肝病。

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摘要

Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many cell populations. Numerous investigations suggest that IL-10 plays a major role in chronic liver diseases. IL-10 gene polymorphisms are possibly associated with liver disease susceptibility or severity. Recombinant human IL-10 has been produced and is currently tested in clinical trials. These trials may give new insights into the immunobiology of IL-10 and suggest that the IL-10/IL-10 receptor system may become a new therapeutic target.

机译：白介素（IL）-10是由许多细胞群体产生的重要的免疫调节细胞因子。许多研究表明，IL-10在慢性肝病中起主要作用。 IL-10基因多态性可能与肝病的易感性或严重性有关。已经生产了重组人IL-10，目前正在临床试验中对其进行测试。这些试验可能会为IL-10的免疫生物学提供新的见解，并提示IL-10 / IL-10受体系统可能成为新的治疗靶标。

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来源
《World Journal of Gastroenterology》 |2006年第11期|P.1681-1685|共5页
作者
Zhang LJ; Wang XZ;
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作者单位

Department of Gastroenterology, Union Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China.;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
Interleukin-10; Chronic liver disease; gene polymorphism; Numerous; 白细胞介素10;

机译：Interleukin-10;Chronic liver disease;gene polymorphism;Numerous;白细胞介素10;

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Interleukin-10 and chronic liver disease.

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