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首页> 外文期刊>World Journal of Gastroenterology >Accuracy of combined PET/CT in image-guided interventions of liver lesions: an ex-vivo study.
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Accuracy of combined PET/CT in image-guided interventions of liver lesions: an ex-vivo study.

机译：PET / CT联合在肝损伤的图像引导干预中的准确性：一项体外研究。

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AIM: Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS: Thirty lesions each of hyperdense, isodense and hypodense attenuation compared to normal liver parenchyma were injected into 15 ex-vivo pig livers. All lesions were composed of the same amounts of gelatine containing 0.5 MBq of (18)F-FDG. Following lesion insertion, an interventional needle was placed in each lesion under CT-guidance solely. After that, a PET/CT study was performed. The localization of the needle within the lesion was assessed for CT alone and PET/CT and the root mean square (RMS) was calculated. Results were compared with macroscopic measurements after lesion dissection serving as the standard of reference. RESULTS: In hypo- and isodense lesions PET/CT proved more accurate in defining the position of the interventional device when compared with CT alone. The mean RMS for CT and PET/CT differed significantly in isodense and hypodense lesions. No significant difference was found for hyperdense lesions. CONCLUSION: Combined FDG-PET/CT imaging provides more accurate information than CT alone concerning the needle position in FDG-PET positive liver lesions. Therefore combined PET/CT might be potentially beneficial not only for localization of an interventional device, but may also be beneficial for guidance in interventional liver procedures.
机译：目的：如果只有CT，在肝脏病变中放置介入设备是一项艰巨的任务。我们调查了组合式PET / CT图像在介入性肝研究中对介入设备定位的潜在好处。方法：与正常肝实质相比，将30个病变分别为高密度，等密度和低密度衰减，分别注入15只离体猪肝脏。所有病变均由含0.5 MBq（18）F-FDG的相同量的明胶组成。病灶插入后，仅在CT引导下将介入针置于每个病灶中。之后，进行了PET / CT研究。仅针对CT评估病灶内针的定位，然后计算PET / CT和均方根（RMS）。将结果与病变解剖后的宏观测量结果进行比较，以作为参考标准。结果：与单独的CT相比，在低渗和等渗性病变中，PET / CT被证明在确定介入装置的位置上更为准确。 CT和PET / CT的平均RMS在等密度和低密度病变中差异显着。高密度病变无明显差异。结论：FDG-PET / CT联合成像可提供比单独CT更准确的FDG-PET阳性肝脏病变中的针头位置信息。因此，组合的PET / CT可能不仅对介入器械的定位潜在有益，而且对介入肝手术的指导也可能有益。

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