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首页> 外文期刊>World Journal of Gastroenterology >Clinico-pathological aspects of colorectal serrated adenomas.
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Clinico-pathological aspects of colorectal serrated adenomas.

机译：大肠锯齿状腺瘤的临床病理特征。

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AIM: To study the association of colorectal serrated adenomas (SAs) with invasive carcinoma, local recurrence, synchronicity and metachronicity of lesions. METHODS: A total of 4,536 polyps from 1,096 patients over an eight-year period (1987-1995) were retrospectively examined. Adenomas showing at least 50% of serrated architecture were called SAs by three reviewing pathologists. RESULTS: Ninety-one (2%) of all polyps were called SAs, which were found in 46 patients. Invasive carcinomas were seen in 3 out of 46 (6.4%) patients, of whom one was a case of familial adenomatous polyposis (FAP). A male preponderance was noted and features of a mild degree of dysplasia were seen in majority (n=75, 83%) of serrated adenomas. Follow-up ranged 1-12 years with a mean time of 5.75 years. Recurrences of SAs were seen in 3 (6.4%) cases, synchronous SAs in 16 (34.8%) cases and metachronous SAs in 9 (19.6%) cases. CONCLUSION: Invasive carcinoma arising in serrated adenoma is rare, accounting for 2 (4.3%) cases studied in this series.
机译：目的：研究结直肠锯齿状腺瘤（SAs）与浸润性癌，病变的局部复发，同步性和异时性的关系。方法：回顾性分析了八年间（1987-1995年）来自1,096名患者的4,536例息肉。三位回顾性病理学家将显示至少50％锯齿状结构的腺瘤称为SA。结果：所有息肉中有91个（占2％）被称为SA，在46例患者中被发现。 46例患者中有3例（6.4％）观察到浸润性癌，其中1例是家族性腺瘤性息肉病（FAP）。注意到男性占优势，并且在大多数（n = 75，83％）锯齿状腺瘤中可见轻度的发育异常。随访时间1-12年，平均时间5.75年。 SAs复发3例（6.4％），同步SAs 16例（34.8％），异时SAs 9例（19.6％）。结论：锯齿状腺瘤引起的浸润性癌很少见，占本系列研究的2例（4.3％）。

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