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首页> 外文期刊>World Journal of Gastroenterology >Clinical profile of gastric cancer in Khuzestan, southwest of Iran.
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Clinical profile of gastric cancer in Khuzestan, southwest of Iran.

机译：伊朗西南部Khuzestan的胃癌临床资料。

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AIM: To analyze the characteristics of epidemiological, clinical and survival patterns among patients with carcinoma of the stomach. METHODS: We retrospectively studied the characteristics of 186 gastric adenocarcinoma patients at Ahwaz Jundishapur University Hospitals (AJSUH) from September 1, 1996 to September 1, 2002. All the patients had histopathologically-confirmed malignancy. Demographic variables, family history of gastric cancer (GC), clinicopathologic characteristics and treatment-related variables were analyzed. Univariate analysis was performed with the log-rank test and multivariate analysis with Cox regression. P<0.05 was considered statistically significant. RESULTS: Male to female ratio was 2.6:1. The mean age was 60.6 years and 14% of the patients were younger than 40 years. Adenocarcinoma, gastric lymphoma, and gastric metastasis were found in 94.5%, 2.3%, and 3% patients, respectively. There was an average of 6-mo delay between the initial symptoms and the diagnosis. Among adenocarcinoma groups, intestinal type was the commonest (55.9%) and the distal third was the most common localization (88.4%). One hundred and thirty-four patients (72.1%) were males. Thirty-one patients (17%) had a family history of GC. Surgery was performed in 90% of patients (non-curative). CONCLUSION: The epidemiological features of GC in south Iran mimic those in high-risk areas. There is a higher frequency of GC in young patients at our institution. Patients are detected and treated after a relatively long delay. Most patients present in advanced stages, which favors a poor overall survival. Family history of GC has a significant problem in our area. Studying the etiology of this cancer in south Iran and earlier diagnosis and subsequent better cares are recommended.
机译：目的：分析胃癌患者的流行病学，临床和生存模式。方法：我们回顾性研究了1996年9月1日至2002年9月1日在Ahwaz Jundishapur University Hospitals（AJSUH）收治的186例胃腺癌患者的特征。所有患者均经组织病理学证实为恶性肿瘤。分析了人口统计学变量，胃癌家族史（GC），临床病理特征和与治疗有关的变量。单因素分析采用对数秩检验，多因素分析采用Cox回归。 P <0.05被认为具有统计学意义。结果：男女之比为2.6：1。平均年龄为60.6岁，其中14％的患者年龄小于40岁。分别在94.5％，2.3％和3％的患者中发现腺癌，胃淋巴瘤和胃转移。最初症状和诊断之间平均有6个月的延迟。在腺癌组中，肠型是最常见的（55.9％），而远端的三分之一是最常见的定位（88.4％）。一百三十四名患者（72.1％）是男性。 31名患者（17％）有胃癌家族史。 90％的患者进行了手术（非治愈性）。结论：伊朗南部地区气相色谱的流行病学特征与高风险地区的相似。在我们机构中，年轻患者发生GC的频率更高。在相对较长的延迟后，对患者进行检测和治疗。大多数患者处于晚期，这有利于较差的总生存期。 GC的家族史在我们地区存在重大问题。建议研究伊朗南部该癌症的病因，并尽早诊断和随后的更好护理。

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