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首页> 外文期刊>World Journal of Gastroenterology >Cytomegalovirus and inflammatory bowel disease: is there a link?
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Cytomegalovirus and inflammatory bowel disease: is there a link?

机译：巨细胞病毒和炎症性肠病：有联系吗？

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摘要

The objective of this report is to give an overall view of the epidemiological, clinical, diagnostic and therapeutic features of Cytomegalovirus (CMV) infection in inflammatory bowel disease (IBD). A review of published reports on this topic was carried out, with particular attention paid to the selection of patients included in studies and the diagnostic methods employed. CMV is frequently associated with IBD. In some cases, CMV infection is associated with a poor outcome but it is not clear which patients are more likely to be affected and in which stage of the disease. The use of anti-viral therapy in IBD is controversial and an empirical study with controls is needed. The natural history of CMV infection related to the development and treatment of IBD has not been clarified but it is important to take it in consideration because of the possibility of viral persistence in the immunocompromised host and viral interaction with the immune system.
机译：本报告的目的是全面了解炎性肠病（IBD）中巨细胞病毒（CMV）感染的流行病学，临床，诊断和治疗特征。对已发表的有关该主题的报告进行了回顾，特别注意研究中所选择的患者的选择和所采用的诊断方法。 CMV通常与IBD相关。在某些情况下，CMV感染与不良预后相关，但尚不清楚哪些患者更可能受到影响以及在疾病的哪个阶段。在IBD中使用抗病毒治疗存在争议，需要进行有控制的经验研究。与IBD的发生和治疗有关的CMV感染的自然史尚未阐明，但考虑到这一点很重要，因为在免疫受损宿主中病毒持续存在以及病毒与免疫系统相互作用的可能性。

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