• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>World Journal of Gastroenterology >Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue.
【24h】

Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue.

机译：益生菌对豚鼠离体组织胃肠蠕动的影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

AIM: To evaluate the intestinal motility changes evoked by 8 bacterial strains belonging to Bifidobacterium, Lactobacillus and Streptococcus genera within the probiotic preparation VSL#3. METHODS: Ileum and proximal colon segments isolated from guinea-pigs were used as a study model. Entire cells and cell fractions (cell debris, cell wall fraction, cytoplasmatic fraction, proteinaceous and non-proteinaceous cytoplasmatic components) of VSL#3 strains and, as controls, Escherichia coli, Salmonella aboni and Bacillus licheniformis were tested in this in vitro model. RESULTS: Among the bacterial cell fractions tested, only the cytoplasmatic fraction modified intestinal motility. Lactobacillus strains stimulated the contraction of ileum segment, whereas all probiotic strains tested induced proximal colon relaxation response. The non-proteinaceous cytoplasmatic components were responsible for the colon relaxation. CONCLUSION: The results obtained in this study suggest that the proximal colon relaxation activity showed by the probiotic bacteria could be one of the possible mechanisms of action by which probiotics exert their positive effects in regulating intestinal motility.
机译：目的：评估益生菌制剂VSL＃3中8种双歧杆菌，乳杆菌和链球菌属细菌引起的肠蠕动变化。方法：从豚鼠中分离出回肠和近端结肠段作为研究模型。在该体外模型中测试了VSL＃3菌株的整个细胞和细胞级分（细胞碎片，细胞壁级分，细胞质级分，蛋白质和非蛋白质细胞质成分）以及作为对照的大肠杆菌，沙门氏沙门氏菌和地衣芽孢杆菌。结果：在所测试的细菌细胞部分中，只有细胞质部分改变了肠蠕动。乳酸杆菌菌株刺激回肠段的收缩，而所有测试的益生菌菌株均引起近端结肠松弛反应。非蛋白质细胞质成分是结肠松弛的原因。结论：本研究结果表明，益生菌所表现出的近端结肠松弛活性可能是益生菌发挥积极作用调节肠道运动的可能机制之一。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号