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首页> 外文期刊>World Journal of Gastroenterology >Reversibility of central neuronal changes in patients recovering from gallbladder stones or acute cholecystitis.
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Reversibility of central neuronal changes in patients recovering from gallbladder stones or acute cholecystitis.

机译：从胆囊结石或急性胆囊炎恢复的患者中枢神经元变化的可逆性。

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AIM: To investigate the referred pain area in patients 2-7 years after cholecystectomy in order to test the hypothesis that neuroplastic changes could give rise to post cholecystectomy pain. METHODS: Forty patients were tested. Twenty five were cholecystectomized due to uncomplicated gallbladder stones and 15 because of acute cholecystitis. Sensitivity to pinprick, heat, cold, pressure and single and repeated electrical stimulation was studied both in the referred pain area and in the control area on the contra lateral side of the abdomen. RESULTS: Five patients still intermittently suffered from pain. But in the objective test of the 40 patients, no statistical significant difference was found between the referred pain area and the control area. CONCLUSION: This study does not support the hypothesis that de novo neuroplastic changes could develop several years after cholecys-tectomy.
机译：目的：调查胆囊切除术后2-7年患者的疼痛部位，以验证神经塑变可能引起胆囊切除术后疼痛的假说。方法：对40名患者进行了测试。 25例因胆囊结石不复杂而进行了胆囊切除术，另15例因急性胆囊炎而进行了胆囊切除术。研究了在指腹疼痛区域和腹部对侧控制区域中对针刺，热，冷，压力以及单次和反复电刺激的敏感性。结果：五名患者仍间歇性地遭受痛苦。但是在对40例患者的客观测试中，在所提及的疼痛区域和对照组之间没有发现统计学上的显着差异。结论：这项研究不支持胆囊切除术后数年可能发生从头神经再生改变的假说。

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