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Microscopic colitis: A retrospective study of clinical presentation in 53 patients.

机译:显微结肠炎:回顾性研究53例患者的临床表现。

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AIM: To evaluate the relationship between symptoms and microscopic colitis (MC) subtypes: to test whether collagenous colitis (CC) and/or lymphocytic colitis (LC) might be related to both constipation and diarrhea. METHODS: A cohort of patients with independently confirmed typical histopathological changes was investigated. Fifty-three patients with histologically proved MC (46 with CC, 7 with LC) were included. The existence of diarrhea or constipation and the co-existence of autoimmune diseases were also investigated and all data were retrospectively analyzed. RESULTS: Twenty-three (43.39%) of MC patients had chronic constipation (20 in CC, 3 in LC patients). Twenty-four (45.28%) of MC patients had autoimmune disease and the diagnosis of autoimmune disease was always prior to MC. Sjogren's syndrome was associated only with the constipation subgroup. CONCLUSION: The Janus face of MC resembles the subgroups of irritable bowel syndrome. The co-existence of autoimmune diseases and MC is confirmed in boththe constipation and diarrhea subgroups.
机译:目的:评估症状与微观结肠炎(MC)亚型之间的关系:测试胶原性结肠炎(CC)和/或淋巴细胞性结肠炎(LC)是否与便秘和腹泻有关。方法:一组独立证实典型组织病理学改变的患者进行了研究。包括53例经组织学证实为MC的患者(CC为46例,LC为7例)。还研究了腹泻或便秘的存在以及自身免疫性疾病的共存,并对所有数据进行了回顾性分析。结果:23名(43.39%)MC患者患有慢性便秘(CC患者20例,LC患者3例)。 MC患者中有二十四名(45.28%)患有自身免疫性疾病,并且自身免疫性疾病的诊断始终在MC之前。干燥综合征仅与便秘亚组有关。结论:MC的Janus面部类似于肠易激综合症的亚组。在便秘和腹泻亚组中都证实了自身免疫性疾病和MC的并存。

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