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首页> 外文期刊>World Journal of Gastroenterology >14)C-urea breath test in patients undergoing anti-tuberculosis therapy.
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14)C-urea breath test in patients undergoing anti-tuberculosis therapy.

机译：14）正在接受抗结核治疗的患者的C尿素呼气试验。

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AIM: Urea breath test (UBT) is a non-invasive diagnostic test for detecting the presence of Helicobacter pylori (H pylori). In this study we evaluated the effect of anti-tuberculosis therapy on the results of (14)C-UBT. METHODS: Patients, with the diagnosis of tuberculosis (TB) who had a positive UBT at the point of starting anti-TB therapy, were included. None had a history of peptic ulcer disease or had taken antibiotics, bismuth compounds and/or PPI in the previous month. (14)C-UBT was repeated at the end of the second month and the end of treatment period and one month after completion of treatment course. RESULTS: Thirty-five patients (23 males) were enrolled. 14C-UBT was negative in all 35 patients (100%) at the end of the second month and remained negative in 30 cases (85.7%) at the end of the treatment course. One month after completion of treatment course, UBT remained negative in 13 patients (37.1%). CONCLUSION: Our report underscores the need for caution while interpreting urea breath test results in patients undergoing anti-TB therapy. Furthermore, the combination of drugs used in this study resulted in H pylori eradication in a minority of patients.
机译：目的：尿素呼气试验（UBT）是一种非侵入性的诊断测试，用于检测幽门螺杆菌（H pylori）的存在。在这项研究中，我们评估了抗结核治疗对（14）C-UBT结果的影响。方法：纳入诊断为结核病（TB）且在开始抗结核治疗时UBT呈阳性的患者。没有人有消化性溃疡病史，或在前一个月服用过抗生素，铋化合物和/或PPI。 （14）C-UBT在第二个月末和治疗期末以及疗程结束后一个月重复进行。结果：35例患者（23例男性）入组。在第二个月末，所有35例患者（14％）的14C-UBT阴性，而在疗程结束时30例（85.7％）阴性。在完成疗程一个月后，UBT仍为13例患者的阴性（37.1％）。结论：我们的报告强调在解释接受抗结核治疗的患者的尿素呼气试验结果时应谨慎行事。此外，本研究中使用的药物组合导致少数患者根除幽门螺杆菌。

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