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首页> 外文期刊>World Journal of Gastroenterology >Unusual clinical course of metachronous melanomas of the upper digestive system.
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Unusual clinical course of metachronous melanomas of the upper digestive system.

机译：上消化系统异时性黑色素瘤的异常临床病程。

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摘要

Melanoma of the gastrointestinal tract is a rare, highly malignant neoplasm of poor prognosis. This is description of an unusual case of surgically treated patient with two metachronous malignant melanomas of the stomach and the esophagus. The former lesion was located in the cardia and effectively treated with R0 total gastrectomy. The latter was recognized after 67 mo and appeared as irregular, flat, pigmented areas located in the mid esophagus. Subtotal esophagectomy via right-sided thoracotomy, laparotomy and left-sided cervicotomy was performed, but neoplastic cells were found in distal margin (R1). Fourteen months after esophagectomy multiple lung metastases were detected. Patient died 2 mo later.
机译：胃肠道黑色素瘤是一种罕见的高度恶性肿瘤，预后不良。这是对患有胃和食道两个异时性恶性黑色素瘤的外科手术患者的不寻常病例的描述。前病变位于the门，并经R0全胃切除术有效治疗。后者在67 mo后被确认，并显示为位于食道中部的不规则，平坦的色素沉着区域。通过右侧胸廓切开术，剖腹术和左侧宫颈切开术进行了部分次食管切除术，但在远端边缘（R1）发现了肿瘤细胞。食管切除术后十四个月发现多处肺转移。患者在2个月后死亡。

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