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首页> 外文期刊>World Journal of Gastroenterology >Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy.
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Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy.

机译：通过双气囊内窥镜检查确定非甾体抗炎药引起的小肠损伤。

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AIM: To clarify clinical features of the NSAID-induced small bowel lesions using a new method of endoscopy. METHODS: This is a retrospective study and we analyzed seven patients with small bowel lesions while taking NSAIDs among 61 patients who had undergone double-balloon endoscopy because of gastro-intestinal bleeding or anemia between September 2000 and March 2004, at Jichi Medical School Hospital in Japan. Neither conventional EGD nor colonoscopy revealed any lesions of potential bleeding sources including ulcerations. Double-balloon endoscopy was carried out from oral approach in three patients, from anal approach in three patients, and from both approaches in one patient. RESULTS: Ulcers or erosions were observed in the ileum in six patients and in the jejunum in one patient, respectively. The ulcers were multiple in all the patients with different features from tiny punched out ulcers to deep ulcerations with oozing hemorrhage or scar. All the patients recovered uneventfully and had full resolution of symptoms after suspension of the drug. CONCLUSION: NSAIDs can induce injuries in the small bowel even in patients without any lesions in both the stomach and colon.
机译：目的：使用一种新的内窥镜检查方法阐明NSAID引起的小肠病变的临床特征。方法：这是一项回顾性研究，我们分析了2000年9月至2004年3月之间因胃肠道出血或贫血而进行了双气囊内镜检查的61例接受NSAID的7例小肠病变患者。日本。传统的EGD或结肠镜检查均未显示任何潜在出血源（包括溃疡）的损害。从三名患者的口腔入路，三名患者的肛门入路和一名患者的两种入路进行双气囊内窥镜检查。结果：6例患者的回肠有溃疡或糜烂，而1例患者的空肠有溃疡或糜烂。从微小的穿孔溃疡到渗出性出血或疤痕的深层溃疡，所有患者的溃疡均具有不同特征。暂停使用该药后，所有患者均康复良好，症状完全缓解。结论：即使在胃和结肠均无任何病变的患者中，非甾体抗炎药也可引起小肠损伤。

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