首页> 外文期刊>World Journal of Gastroenterology >Multidimensional assessment of neuro-psychiatric symptoms in patients with low-grade hepatic encephalopathy: A clinical rating scale.
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Multidimensional assessment of neuro-psychiatric symptoms in patients with low-grade hepatic encephalopathy: A clinical rating scale.

机译:低度肝性脑病患者神经精神症状的多维评估:临床评估量表。

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AIM: To evaluate the feasibility of a new clinical rating scale for a standardized assessment of cirrhosis-associated neuro-psychiatric symptoms. METHODS: Forty patients with liver cirrhosis (LC, with or without low-grade hepatic encephalopathy) were invest-igated using a clinical neuro-psychiatric rating scale based on a comprehensive list of neurological, psychomotor, cognitive, affective, behavioral symptoms, and symptoms of disturbed bioregulation. RESULTS: The analysis revealed that the majority of cirrhotic patients showed, besides characteristic neurological symptoms of hepatic encephalopathy, various psychomotor, affective and bioregulatory symptoms (disturbed sleep and sexual dysfunction). Patients were impaired in the following subscales: sleep and biorhythm disorder (75.0% of patients), Parkinsonoid symptoms (25.0%), affective symptoms (17.5%), and psychomotor retardation (12.5%). The increase of total neuro-psychiatric clinical score was significantly associated with the degree of hepatic enceph-alopathy. CONCLUSION: This study suggests that a substantial number of patients with LC and low-grade hepatic encephalopathy manifest various clinical neuro-psychiatric symptoms. The use of a rating scale, which explores clinical dimensions of hepatic encephalopathy, would improve the management of patients with LC.
机译:目的:评估新的临床评分量表对肝硬化相关的神经精神症状进行标准化评估的可行性。方法:根据临床神经精神病学评定量表,根据神经,精神运动,认知,情感,行为症状和症状的综合清单,对40例肝硬化(LC,伴或不伴低度肝性脑病)患者进行调查。生物调节紊乱。结果:分析显示,大多数肝硬化患者除了表现出肝性脑病的典型神经系统症状外,还表现出各种精神运动,情感和生物调节症状(睡眠障碍和性功能障碍)。患者的以下分量表受损:睡眠和生物节律障碍(占患者75.0%),帕金森氏症状(占25.0%),情感症状(占17.5%)和精神运动发育迟缓(占12.5%)。总神经精神病学临床分数的增加与肝性脑病的程度显着相关。结论:这项研究表明大量LC和低度肝性脑病患者表现出各种临床神经精神症状。探索肝脏肝病临床表现的评分量表的使用将改善LC患者的管理。

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