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首页> 外文期刊>World Journal of Gastroenterology >Use of endoscopic naso-pancreatic drainage in the treatment of severe acute pancreatitis
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Use of endoscopic naso-pancreatic drainage in the treatment of severe acute pancreatitis

机译：内镜鼻胰管引流术治疗重症急性胰腺炎

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AIM: To review the experience on the use of endoscopic nasopancreatic drainage (ENPD) in the treatment of severe acute pancreatitis (SAP). METHODS: Since March 1998, under the regular management of SAP with non-operative method, ENPD has been randomly used in 14 patients. The average age of the patients was 41.3+-15.9 (years), with 8 males and 6 females. The time from onset to admission was 32.9+-22.8 (hours). 8 cases were found to have gallbladder stone. The daily output of pancreatic fluid was measured. The body temperature, heart rate, WBC count, blood glucose, blood calcium, PaO_2, blood and urine levels of amylase were detected on the fifth day and compared with their respective data on the first day. Therapeutic results and hospitalization times were recorded. RESULTS: The time of drainage was 7.3+-4.0 days. The daily drainage outputs of the first five days were 236.4+-176.6, 287.1+-164.7, 284.6+-216.4,435.0+-357.8 and 377.8+-223.8 ml, respectively. The decreases in body temperature, heart rate, WBC counts, blood and urine levels of amylase and the increase in PaO_2 were significant on the fifth day when compared with those on the first day. Infection of pancreatic necrosis was found in one patient and controlled by anti-infectives. 6 out of 8 patients with gallbladder stone were operated during hospital stay. All patients were cured and diischarged and the average hospital stay was 28.1+-11.6 days. CONCLUSION: ENPD is an effective method for the drainage of pancreatic fluid and might have an important role in the treatment of SAP. Further observation, comparison and summary by this method are worthy to be considered.
机译：目的：回顾内镜鼻胰管引流术（ENPD）治疗严重急性胰腺炎（SAP）的经验。方法：自1998年3月以来，在非手术方式SAP的常规治疗下，ENPD已随机用于14例患者。患者的平均年龄为41.3 + -15.9（年），男8例，女6例。从发病到入院的时间为32.9 + -22.8（小时）。发现8例胆囊结石。测量胰液的每日产量。在第五天检测到的体温，心率，WBC计数，血糖，血钙，PaO_2，血液和尿液中的淀粉酶水平，并与第一天的数据进行比较。记录治疗结果和住院时间。结果：引流时间为7.3 + -4.0天。前五天的每日排水量分别为236.4 + -176.6 ml，287.1 + -164.7、284.6 + -216.4、435.0 + -357.8和377.8 + -223.8 ml。与第一天相比，第五天的体温，心率，WBC计数，淀粉酶的血液和尿液水平下降以及PaO_2的增加显着。在一名患者中发现了胰腺坏死的感染，并由抗感染药控制。 8例胆囊结石患者中有6例在住院期间进行了手术。所有患者均治愈并出院，平均住院时间为28.1 + -11.6天。结论：ENPD是一种有效的胰液引流方法，可能在SAP的治疗中起重要作用。这种方法的进一步观察，比较和总结值得考虑。

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