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首页> 外文期刊>World Journal of Gastroenterology >Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15
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Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15

机译：熊果酸和齐墩果酸对人结肠癌细胞HCT15的影响

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CONCLUSION: UA and OA have significant anti-tumor activity. The effect of UA is stronger than that of OA. The possible mechanism of action is that both drugs have an inhibitory effect on tumor cell proliferation through cell-cycle arrest. AIM: Ursolic acid (UA) and oleanolic acid (OA) are triperpene acids having a similar chemical structure and are distributed wildly in plants all over the world. In recent years, it was found that they had marked anti-tumor effects. There is little literature currently available regarding their effects on colon carcinoma cells. The present study was designed to investigate their inhibitory effects on human colon carcinoma cell line HCT15.
机译：结论：UA和OA具有显着的抗肿瘤活性。 UA的效果比OA的效果更强。可能的作用机制是两种药物均通过细胞周期停滞对肿瘤细胞增殖具有抑制作用。目的：熊果酸（UA）和齐墩果酸（OA）是具有相似化学结构的三萜烯酸，广泛分布于世界各地的植物中。近年来，发现它们具有显着的抗肿瘤作用。目前关于它们对结肠癌细胞的作用的文献很少。本研究旨在研究它们对人结肠癌细胞系HCT15的抑制作用。

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