Antitumor activities of human autologous cytokine- induced killer (CIK) cells against hepatocellular carcinoma cells in vitro and in vivo

Fu-Sheng Wang; Ming-Xu Liu; Bing Zhang

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Antitumor activities of human autologous cytokine- induced killer (CIK) cells against hepatocellular carcinoma cells in vitro and in vivo

机译：人自体细胞因子诱导的杀伤（CIK）细胞在体外和体内对肝癌细胞的抗肿瘤活性

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CONCLUSION: Autologous CIK cells are of highly efficient cytotoxic effector cells against primary hepatocellular carcinoma cells and might serve as an alternative adoptive therapeutic strategy for HCC patients. AIM: To characterize the anticancer function of cytokine- induced killer cells (CIK) and develop an adoptive immunotherapy for the patients with primary hepatocellular carcinoma (HCC), we evaluated the proliferation rate, phenotype and the antitumor activity of human CIK cells from healthy donors and HCC patients in vitro and in vivo.

机译：结论：自体CIK细胞是针对原发性肝癌细胞的高效细胞毒性效应细胞，并可能作为肝癌患者的替代性过继治疗策略。目的：为表征细胞因子诱导的杀伤细胞（CIK）的抗癌功能并开发针对原发性肝细胞癌（HCC）患者的过继免疫疗法，我们评估了来自健康供体的人CIK细胞的增殖率，表型和抗肿瘤活性和HCC患者的体内和体外。

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来源
《World Journal of Gastroenterology》 |2002年第3期|p.464-468|共5页
作者
Fu-Sheng Wang; Ming-Xu Liu; Bing Zhang;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
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2. Anti-tumor activity of ex vivo expanded cytokine-induced killer cells against human hepatocellular carcinoma. [J] . Kim HM, Lim J, Yoon YD, International immunopharmacology . 2007,第13期

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3. Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responses in Vitro [J] . Li-Hong Lv, Yun-Le Wan, Yan Lin, The Journal of biological chemistry . 2012,第19期

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4. Antitumor Activity of Escin in Mice Cervical Carcinoma U_(14) in vivo and Human Cervical Carcinoma Hela Cell Line in vitro [C] . Xueying Zhou, Changhai Wang, Fenghua Fu The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议）论文集 . 2009

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6. Antitumor activities of human autologous cytokine-induced killer (CIK) cells against hepatocellular carcinoma cells in vitro and in vivo [O] . Fu-Sheng Wang, Ming-Xu Liu, Bing Zhang, 2002

机译：人自体细胞因子诱导的杀伤（CIK）细胞在体外和体内对肝癌细胞的抗肿瘤活性
7. Antitumor activities of human autologous cytokine-induced killer (CIK) cells against hepatocellular carcinoma cellsin vitroandin vivo [O] . Fu-Sheng Wang 2002

机译：人体自体细胞因子诱导杀手（CIK）细胞对肝细胞癌细胞蛋白体内体内的抗肿瘤活动
8. Human T Helper Cells Specific for Antigens of Typhus Group Rickettsiae Enhance Natural Killer Cell Activity In vitro [R] . Carl, M., Martin, E. E., Dasch, G. A. 1986

机译：特异于斑疹伤寒组立克次体抗原的人T辅助细胞在体外增强自然杀伤细胞活性

Antitumor activities of human autologous cytokine- induced killer (CIK) cells against hepatocellular carcinoma cells in vitro and in vivo

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