首页> 外文期刊>World Journal of Gastroenterology >Inhibitory effects of RRR-α-tocopheryl succinate on benzo (a) pyrene (B(a)P)-induced forestomach carcinogenesis in female mice
【24h】

Inhibitory effects of RRR-α-tocopheryl succinate on benzo (a) pyrene (B(a)P)-induced forestomach carcinogenesis in female mice

机译:RR-α-生育酚琥珀酸酯对雌性小鼠苯并(a)((B(a)P)诱导的前胃癌致癌作用的抑制作用

获取原文
获取原文并翻译 | 示例
           

摘要

AIM To study the inhibitory effects of VES (RRR-α-tocopheryl Succinate, VES), a derivative of natural Vitamin E, on benzo (a) pyrene (B(a)P)-induced forestomach tumor in female mice. METHODS The model of B (a) P-induced Forestomach tumor was established according to The methods of Wattenberg with slight Modifications. One hundred and eightly female Mice (6 weeks old) were divided into six groups Equally; negative control (Succinic acid), Vehicle control (Succinate + B(a)P), positive Control (B(a)P), high VES (2.5 g/kg.b.w+B(a) P), low VES(1.25 g/kg. B. W +B (a) P) ig as well As VES by ip (20 mg/kg. B. W + B (a) P). Except The negative control group, the mice were Administrated with B(a)P ig.
机译:目的研究天然维生素E的衍生物VES(RRR-α-生育酚琥珀酸酯,VES)对苯并(a)pyr(B(a)P)诱导的雌性小鼠胃癌的抑制作用。方法根据Wattenberg的方法(稍作修改)建立B(a)P诱导的Forestomach肿瘤模型。一百零八只雌性小鼠(6周龄)被分为六组。阴性对照(琥珀酸),媒介对照(琥珀酸+ B(a)P),阳性对照(B(a)P),高VES(2.5 g / kg.b.w + B(a)P),低VES (1.25 g / kg。B. W + B(a)P)ig以及VES by ip(20 mg / kg。B. W + B(a)P)。除阴性对照组外,给小鼠施用B(a)P ig。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号