首页> 外文期刊>World Journal of Gastroenterology >Adhesion molecule and proinflammatory cytokine gene expression in hepatic sinusoidal endothelial cells following cecal ligation and puncture
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Adhesion molecule and proinflammatory cytokine gene expression in hepatic sinusoidal endothelial cells following cecal ligation and puncture

机译:盲肠结扎穿刺后肝窦窦内皮细胞黏附分子和促炎细胞因子基因的表达

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摘要

Multiple organ dysfunction syndrome (MODS) si thought to be a fequent consequence of sepsis~[1-3]. Despite substantial advances in our knowledge and Understanding of the basic pathophysiologic Mechanisms~[4-7], in critically ill patients infections And sepsis are still associated with a high Mortality~[8,9]. There is evidence that the Development of tissue damage in sepsis and shock is Closely associated with the release of an ever- Increasing number of mediators and accumulation of Neutrophils at the sites of infection or injury~[10,11].
机译:多器官功能障碍综合症(MODS)被认为是败血症〜[1-3]的后遗症。尽管我们对基本的病理生理机制〜[4-7]的认识和理解有了长足的进步,但在重症患者中,感染和败血症仍与高死亡率有关[8,9]。有证据表明败血症和休克中组织损伤的发展与感染或损伤部位中越来越多的介质释放和中性粒细胞积累密切相关[10,11]。

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