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首页> 外文期刊>World Journal of Gastroenterology >Effect of cholecystokinin and secretin on contractile activity of isolated gastric muscle strips in guinea pigs
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Effect of cholecystokinin and secretin on contractile activity of isolated gastric muscle strips in guinea pigs

机译:胆囊收缩素和促胰液素对豚鼠离体胃肌条收缩活性的影响

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摘要

AIM To study the effect of cholecystokinin- octapeptide (CCK-8) and secretin on contractile activity of isolated gastric muscle strips in guinea pigs. METHODS Each isolated gastric muscle strip Was suspended in a tissue chamber containing 5 mL Krebs solution constantly warmed by water jacked at 37 deg. C and supplied with a mixed gas of 95/100 O_2 and 5/100 CO_2. After incubating for 1 h under 1 g tension, varied concentrations of CCK- 8 and secretin were added respectively in the tissue chamber and the contractile response was measured isometrically on ink-writing recorders.
机译:目的研究胆囊收缩素-八肽(CCK-8)和促胰液素对豚鼠离体胃肌条收缩活性的影响。方法将每条孤立的胃肌条悬吊在含有5 mL Krebs溶液的组织室中,该溶液不断地在37度顶升的水中加热。并提供95/100 O_2和5/100 CO_2的混合气体。在1 g张力下孵育1 h后,分别在组织室中添加不同浓度的CCK-8和促胰液素,并在墨水记录仪上等距测量收缩反应。

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