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Alterations in gastric mucin synthesis by Helicobacter pylori

机译:幽门螺杆菌在胃粘蛋白合成中的改变

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摘要

Helicobacter pylori is recognized as a cause of chronic active gastritis, gastric and duodenal ulcers, and gastric cancer, though the mechanisms of pathogenesis for H. Pylori-associated diseases are not yet well understood The ecological niche to which H. Pylori is well-adapted is The mucous layer of the human gastric antrum, which has Mucin glycoproteins as major constituents. Mucins, high- Molecular weight carbohydrate-rich glycoproteins that coat The surface of the stomach and are secreted into the lumen, Function to protect the stomach and could be important in H. pylori colonization.
机译:幽门螺杆菌被公认为是慢性活动性胃炎,胃和十二指肠溃疡以及胃癌的病因,尽管尚不了解幽门螺杆菌相关疾病的发病机理,但幽门螺杆菌的适应性很强。是人胃窦的粘液层,它以粘蛋白糖蛋白为主要成分。粘蛋白,高分子量的富含碳水化合物的糖蛋白,覆盖在胃表面并被分泌到管腔中,起到保护胃的作用,在幽门螺杆菌定植中可能很重要。

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