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首页> 外文期刊>Bulletin of the National Research Centre >Immunological Investigation of Urinary Proteins in Algerian Diabetic Patients
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Immunological Investigation of Urinary Proteins in Algerian Diabetic Patients

机译：阿尔及利亚糖尿病患者尿蛋白的免疫学调查

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摘要

115 juvenile and adult algerian diabetic patients were subjected for urine proteins investigation by gel electrophoresis and the immunoelectrophoresis. The results obtained were correlated with age of patients; duration of the disease; sex and type of treatment. In patients with diabetes for less than 5 years and proteinuria not more than 100 mg/dl, albumin; transferrin and ceruloplasmin were the protein components mostly excreted in urine and the proteinuria in such cases was described as selective. In patients with diabetes of more than 5 years and proteinuria exceeding 100 mg/dl, additional relatively high molecular weight proteins including IgA and IgG were detected and the proteinuria in such cases can be considered as non selective. It is concluded that, selective proteinuria was encountered in young males as well as the same number of young females at the same age, whereas the non-selective proteinuria seems to be of higher frequency among adult female than adult male diabetics and it can be considered as a sign of advanced nephrotic ailment that would require much more intensive medical care.
机译：通过凝胶电泳和免疫电泳对115名青少年和成年阿尔及利亚糖尿病患者进行尿蛋白检查。获得的结果与患者年龄相关。疾病持续时间；性别和治疗类型。糖尿病少于5年且蛋白尿不超过100 mg / dl的白蛋白患者;转铁蛋白和铜蓝蛋白是尿液中大部分排泄的蛋白质成分，这种情况下的蛋白尿被描述为选择性的。在患有5年以上且蛋白尿超过100 mg / dl的糖尿病患者中，还检测到其他相对较高分子量的蛋白，包括IgA和IgG，在这种情况下，蛋白尿可被视为非选择性的。结论是，在相同年龄的年轻男性以及相同数量的年轻女性中都遇到了选择性蛋白尿，而成年女性中非选择性蛋白尿的发生率似乎比成年男性糖尿病患者高，可以考虑作为晚期肾病疾病的征兆，这将需要更深入的医疗护理。

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