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Bioactive glass-ceramic scaffolds: Processing and properties

机译:生物活性玻璃陶瓷支架:加工和性能

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摘要

Bioactive glasses and related bioactive glass-ceramics have been used for over three decades in biomedical applications such as bulk, particulate, or coatings materials. More recently, highly porous bioactive glass-ceramic scaffolds for bone-tissue engineering have also been developed from selected compositions of bioactive glasses. Current bioactive glass-ceramic scaffolds are characterized by an open porous network, high bioactivity, and mechanical properties similar to those of trabecular bone. This article reviews the latest achievements in the development of porous bioactive glass-ceramics intended for bone-tissue engineering applications, highlighting the fabrication technologies and scaffold properties. Improvements in the mechanical properties of bioactive glass-ceramic scaffolds exhibiting high bioactivity have been achieved by different approaches in the last 10 years. Relevant long-term in vivo studies are required to confirm the suitability of such bioactive glass-ceramic scaffolds in clinical applications.
机译:生物活性玻璃和相关的生物活性玻璃陶瓷已经在生物医学应用中使用了三十多年,例如块状,颗粒状或涂层材料。最近,还从选定的生物活性玻璃组合物中开发出了用于骨组织工程的高度多孔的生物活性玻璃陶瓷支架。当前的生物活性玻璃陶瓷支架的特征在于开放的多孔网络,高生物活性和类似于小梁骨的机械性能。本文回顾了用于骨组织工程应用的多孔生物活性玻璃陶瓷的最新发展成果,重点介绍了制造技术和支架性能。在过去的十年中,已经通过不同的方法实现了表现出高生物活性的生物活性玻璃陶瓷支架的机械性能的改善。需要相关的长期体内研究来确认这种生物活性玻璃陶瓷支架在临床应用中的适用性。

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  • 来源
    《MRS bulletin》 |2017年第3期|226-232|共7页
  • 作者单位

    Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomat, Erlangen, Germany;

    Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomat, Erlangen, Germany;

    Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomat, Erlangen, Germany|Friedrich Alexander Univ Erlangen Nurnberg, Biomat, Erlangen, Germany;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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