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Development of systemic lupus erythematosus in an elderly male hemodialysis patient with pleuritis

机译:老年男性胸膜炎血液透析患者系统性红斑狼疮的发生

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摘要

This report describes a 70-year-old man who developed systemic lupus erythematosus (SLE) during treatment with maintenance hemodialysis. At initiation of maintenance dialysis, the etiology of end-stage renal disease (ESRD) was diabetic nephropathy and no clinical symptom or laboratory data suggested SLE. Fever, pleural effusion that did not respond to ultrafiltration, and immunological findings such as low complement and elevated anti-double-strand DNA antibody level appeared 4 years after maintenance dialysis initiation. Immunosuppressive therapy with corticosteroids improved these abnormalities remarkably. This case underscores the necessity of considering SLE in the differential diagnosis of pleural effusion with male ESRD patients, even if another etiology of ESRD exists.
机译:该报告描述了一名70岁的男子,他在维持性血液透析治疗期间发生了系统性红斑狼疮(SLE)。在开始维持性透析时,终末期肾脏疾病(ESRD)的病因是糖尿病性肾病,没有临床症状或实验室数据提示SLE。维持透析开始后4年出现发烧,对超滤无反应的胸腔积液,以及免疫学发现,例如补体低和抗双链DNA抗体水平升高。皮质类固醇的免疫抑制疗法显着改善了这些异常。该病例强调,即使存在ESRD的另一种病因,也需要在男性ESRD患者的胸腔积液的鉴别诊断中考虑SLE。

著录项

  • 来源
    《CEN Case Reports》 |2013年第1期|46-48|共3页
  • 作者单位

    Department of Nephrology and Endocrinology Graduate School of Medicine The University of Tokyo">(1);

    Department of Nephrology and Endocrinology Graduate School of Medicine The University of Tokyo">(1);

    Department of Nephrology and Endocrinology Graduate School of Medicine The University of Tokyo">(1);

    Department of Allergy and Rheumatology Graduate School of Medicine The University of Tokyo">(2);

    Department of Nephrology and Endocrinology Graduate School of Medicine The University of Tokyo">(1);

    Department of Allergy and Rheumatology Graduate School of Medicine The University of Tokyo">(2);

    Department of Nephrology and Endocrinology Graduate School of Medicine The University of Tokyo">(1);

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Systemic lupus erythematosus; Elderly male; Hemodialysis; Pleuritis;

    机译:系统性红斑狼疮;老年男性;血液透析;胸膜炎;

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