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首页> 外文期刊>Chemical Senses >A Complex Relationship among Chemical Concentration, Detection Threshold, and Suprathreshold Intensity of Bitter Compounds
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A Complex Relationship among Chemical Concentration, Detection Threshold, and Suprathreshold Intensity of Bitter Compounds

机译：苦味化合物的化学浓度，检测阈值和超阈值强度之间的复杂关系

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摘要

Detection thresholds and psychophysical curves were established for caffeine, quinine-HCl (QHCl), and propylthiouracil (PROP) in a sample of 33 subjects (28 female mean age 24 ± 4). The mean detection threshold (±standard error) for caffeine, QHCl, and PROP was 1.2 ± 0.12, 0.0083 ± 0.001, and 0.088 ± 0.07 mM, respectively. Pearson product–moment analysis revealed no significant correlations between detection thresholds of the compounds. Psychophysical curves were constructed for each bitter compound over 6 concentrations. There were significant correlations between incremental points of the individual psychophysical curves for QHCl and PROP. Regarding caffeine, there was a specific concentration (6 mM) below and above which the incremental steps in bitterness were correlated. Between compounds, analysis of psychophysical curves revealed no correlations with PROP, but there were significant correlations between the bitterness of caffeine and QHCl at higher concentrations on the psychophysical curve (P < 0.05). Correlation analysis of detection threshold and suprathreshold intensity within a compound revealed a significant correlation between PROP threshold and suprathreshold intensity (r = 0.46–0.4, P < 0.05), a significant negative correlation for QHCl (r = ?0.33 to ?0.4, P < 0.05), and no correlation for caffeine. The results suggest a complex relationship between chemical concentration, detection threshold, and suprathreshold intensity.
机译：在33名受试者（28名女性平均年龄为24±4）的样本中，建立了咖啡因，奎宁-HCl（QHCl）和丙基硫尿嘧啶（PROP）的检测阈值和心理生理曲线。咖啡因，QHCl和PROP的平均检测阈值（±标准误差）分别为1.2±0.12、0.0083±0.001和0.088±0.07 mM。皮尔逊产物矩分析表明，化合物的检测阈值之间无显着相关性。为每种苦味化合物建立了6种浓度以上的心理生理曲线。 QHCl和PROP的个体心理生理曲线的增量点之间存在显着的相关性。关于咖啡因，存在一个特定的浓度（6 mM），该浓度低于和高于该浓度，这与苦味的增加步骤相关。在化合物之间，对心理生理曲线的分析显示与PROP无相关性，但在心理生理曲线上较高浓度的咖啡因和QHCl之间存在显着相关性（P <0.05）。化合物中检测阈值和阈上强度的相关分析显示，PROP阈值与阈上强度之间存在显着相关性（r = 0.46-0.4，P <0.05），与QHCl呈显着负相关（r =？0.33至？0.4，P < 0.05），与咖啡因无关。结果表明化学浓度，检测阈值和超阈值强度之间存在复杂的关系。

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  • 来源
    《Chemical Senses》 |2007年第3期|245-253|共9页
  • 作者

    Russell S.J. Keast1 and Jessica Roper2;

  • 作者单位

    School of Exercise and Nutrition Sciences Deakin University 221 Burwood Highway Burwood Victoria 3125 Australia;

    RMIT University PVC Science Engineering Technology Applied Sciences Melbourne Victoria 3001 Australia;

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