Au Nanowire-on-Film SERRS Sensor for Ultrasensitive Hg2+ Detection?

Taejoon Kang; Dr. Seung Min Yoo; Dr. Ilsun Yoon; Sangyeop Lee; Prof. Jaebum Choo; Sang Yup Lee; Prof. Bongsoo Kim

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Au Nanowire-on-Film SERRS Sensor for Ultrasensitive Hg2+ Detection?

机译：用于超灵敏Hg 2 + 检测？的金纳米线上SERRS传感器

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摘要

We report an ultrasensitive and selective single nanowire-on-film (SNOF) surface-enhanced resonance Raman scattering (SERRS) sensor for Hg2+ detection based on structure-switching double stranded DNAs (dsDNAs). Binding of Hg2+ induces conformational changes of the dsDNAs and let a Raman reporter get close to the SNOF structure, thereby turning on SERRS signal. The well-defined SNOF structure provides a detection limit of 100 pM with improved accuracy in Hg2+ detection. This sensor is stable over a considerable amount of time and reusable after simple treatment. Since this SNOF sensor is composed of a single Au NW on a film, development of a multiplex sensor would be possible by employing NWs modified by multiple kinds of aptamers.

机译：我们报告了基于结构转换双链DNA（dsDNA）的Hg 2 + 检测的超灵敏且选择性的单纳米膜薄膜（SNOF）表面增强共振拉曼散射（SERRS）传感器。 Hg 2 + 的结合诱导dsDNA的构象变化，并使拉曼报告分子接近SNOF结构，从而打开SERRS信号。明确定义的SNOF结构提供了100 pM的检测限，提高了Hg 2 + 的检测精度。该传感器可在相当长的时间内保持稳定，并且经过简单处理即可重复使用。由于该SNOF传感器由胶片上的单个Au NW组成，因此通过使用由多种适体修饰的NW可以开发多重传感器。

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来源
《Chemistry - A European Journal》 |2011年第7期|2211-2214|共4页
作者
Taejoon Kang; Dr. Seung Min Yoo; Dr. Ilsun Yoon; Sangyeop Lee; Prof. Jaebum Choo; Sang Yup Lee; Prof. Bongsoo Kim;
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作者单位

Department of Chemistry KAIST Daejeon 305-701 (Korea) Fax: (+82) 42-350-2810;

Department of Chemical and Biomolecular Engineering (BK21 Program) KAIST Daejeon 305-701 (Korea);

Department of Bio-nano Engineering Hanyang University Ansan 426-791 (Korea);

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原文格式 PDF
正文语种 eng
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关键词
DNA; gold; mercury; nanowires; surface-enhanced Raman scattering;

机译：DNA;金;汞;纳米线;表面增强拉曼散射;

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1. Au nanowire-on-film SERRS sensor for ultrasensitive Hg~(2+) detection [J] . Kang T., Yoo S.M., Yoon I., Chemistry: A European journal . 2011,第7期

机译：用于超灵敏Hg〜（2+）检测的金纳米线薄膜SERRS传感器
2. Ultrasensitive electrochemical sensor for Hg2+ by using hybridization chain reaction coupled with Ag@Au core-shell nanoparticles [J] . Li Zongbing, Miao Xiangmin, Xing Ke, Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices . 2016,第Null期

机译：杂交链反应与Ag @ Au核壳纳米粒子耦合的Hg2 +超灵敏电化学传感器
3. [5] Helicene-rhodamine 6 G hybrid-based sensor for ultrasensitive Hg2+ detection and its biological applications [J] . Petdum Anuwut, Faichu Natchawat, Sirirak Jitnapa, Journal of Photochemistry and Photobiology, A. Chemistry . 2020,第1期

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4. Dye Coded Nanoparticles as SERRS Labels for Ultrasensitive Detection of Proteins and Antibodies [C] . R. Stevenson, R.J. Stokes, A. Ingram, NSTI BioNano Conference and Trade Show . 2008

机译：染料编码纳米颗粒作为SERRS标记，用于超声检测蛋白质和抗体
5. Simple Colorimetric Detection of Hg2+ in Simulated Urine, HSA, and Water Samples Using L-Cysteine Gold Nanoparticles (AuNPs) [D] . Kumah, Philip Selasi. 2018

机译：使用L-半胱氨酸金纳米粒子（AuNPs）进行比色法检测尿液，HSA和水样中Hg2 +的简单比色检测
6. Binding Affinity of a Highly Sensitive Au/Ag/Au/Chitosan-Graphene Oxide Sensor Based on Direct Detection of Pb2+ and Hg2+ Ions [O] . Nur Hasiba Kamaruddin, Ahmad Ashrif A. Bakar, Nadhratun Naiim Mobarak, 2017

机译：基于直接检测Pb2 +和Hg2 +离子的高灵敏度Au / Ag / Au /壳聚糖-氧化石墨烯传感器的结合亲和力
7. Selectable Ultrasensitive Detection of Hg2+ with Rhodamine 6G-Modified Nanoporous Gold Optical Sensor [O] . Zheng Wang, Min Yang, Chao Chen, 2016

机译：用罗丹明6G改进的纳米多孔金光学传感器可选择的超敏检测HG2 +

Au Nanowire-on-Film SERRS Sensor for Ultrasensitive Hg2+ Detection?

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