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Candle soot derived carbon nanoparticles: Assessment of physico-chemical properties, cytotoxicity and genotoxicity

机译：蜡烛烟灰衍生的碳纳米颗粒：物理化学性质，细胞毒性和遗传毒性的评估

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摘要

In this study, an evaluation of physico-chemical properties, cytotoxicity and genotoxicity of candle soot derived carbon nanoparticles (CNPs) was carried out. Several physico-chemical characterizations including scanning electron microscopy, transmission electron microscope, Brunauer-Emmet-Teller surface area and pore-size distribution, X-ray diffraction, Fourier transform infrared and Raman spectroscopy were implemented to characterize prepared CNPs. Propidium iodide uptake, reactive oxygen species assay and trypan blue exclusion and comet assay tests were executed to determine the toxicity of CNPs. It is found that the CNPs have insignificant cytotoxicity and genotoxicity and could be used in diverse biological and environmental applications as an alternative to expensive less toxic carbon materials. (C) 2018 Elsevier Ltd. All rights reserved.
机译：在这项研究中，进行了蜡烛烟灰衍生碳纳米粒子（CNPs）的理化特性，细胞毒性和遗传毒性的评估。进行了几个物理化学表征，包括扫描电子显微镜，透射电子显微镜，Brunauer-Emmet-Teller表面积和孔径分布，X射线衍射，傅立叶变换红外光谱和拉曼光谱，以表征所制备的CNP。进行碘化丙锭摄取，活性氧种类测定以及锥虫蓝排除和彗星测定试验以确定CNP的毒性。发现CNP具有微不足道的细胞毒性和基因毒性，并且可以作为昂贵的毒性较小的碳材料的替代物用于多种生物学和环境应用中。 （C）2018 Elsevier Ltd.保留所有权利。

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