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Potential genotoxic effects of melted snow from an urban area revealed by the Allium cepa test

机译：葱属cepa试验揭示了市区融雪的潜在遗传毒性效应

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摘要

The presence of well-known atmospheric pollutants is regularly screened for in large towns but knowledge about the effects of mixtures of different pollutants and especially their genotoxic potential is largely missing. Since falling snow collects pollutants from the air, melted snow samples could be suitable for evaluating potential genotoxicity. For this purpose the Allium cepa anaphase-telophase test was used to analyse melted snow samples from Belgrade, the capital city of Serbia. Samples of snow were taken at two sites, characterized by differences in pollution intensity, in three successive years. At the more polluted site the analyses showed a very high degree of both toxicity and genotoxicity in the first year of the study corresponding to the effects of the known mutagen used as the positive control. At the other site the situation was much better but not without warning signals. The results showed that standard analyses for the presence of certain contaminants in the air do not give an accurate picture of the possible consequences of urban air pollution because the genotoxic potential remains hidden. The A cepa test has been demonstrated to be very convenient for evaluation of air pollution through analyses of melted snow samples.
机译：在大型城镇中，定期检查是否存在知名的大气污染物，但对于各种污染物的混合物的影响，尤其是其遗传毒性的潜力，人们所知甚少。由于落雪会从空气中收集污染物，因此融化的积雪样本可能适合评估潜在的遗传毒性。为此，使用了洋葱头孢虫后期-末期试验来分析来自塞尔维亚首都贝尔格莱德的融雪样本。连续三年在两个地点采集了雪样，其特征是污染强度不同。在污染较严重的地点，分析显示，在研究的第一年，毒性和基因毒性都非常高，这与已知的诱变剂用作阳性对照的效果相对应。在另一个站点，情况要好得多，但并非没有警告信号。结果表明，对空气中某些污染物的存在进行标准分析并不能准确反映出城市空气污染的可能后果，因为其潜在的遗传毒性仍然存在。事实证明，通过分析融化的雪样，A cepa测试对于评估空气污染非常方便。

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  • 来源
    《Chemosphere》 |2009年第10期|1344-1347|共4页
  • 作者

    Jelena Blagojevic; Gorana Stamenkovic; Mladen Vujosevic;

  • 作者单位

    Department of Genetic Research, Institute for Biological Research 'SiniSa Stankovic', University of Belgrade' Bulevar despota Stefana 142, 11060 Belgrade, Serbia;

    Department of Genetic Research, Institute for Biological Research 'SiniSa Stankovic', University of Belgrade' Bulevar despota Stefana 142, 11060 Belgrade, Serbia;

    Department of Genetic Research, Institute for Biological Research 'SiniSa Stankovic', University of Belgrade' Bulevar despota Stefana 142, 11060 Belgrade, Serbia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    allium cepa anaphase-telophase test; genotoxicity; melted snow; urban pollution;

    机译：洋葱头皮期末期试验;遗传毒性融雪城市污染;

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