...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chemosphere >Environmental fate of the anthelmintic ivermectin in an aerobic sediment/water system
【24h】

Environmental fate of the anthelmintic ivermectin in an aerobic sediment/water system

机译：有氧沉积物/水系统中驱虫性伊维菌素的环境命运

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This study investigated the long-term fate of ~3H-ivermectin and its metabolites in aerobic sediment/ water systems. Total radioactivity in sediment and water was measured by Liquid Scintillation Counting and Radio-HPLC was used for determination of transformation products.rnThe test system, containing a cooling and a water trap, showed excellent applicability for studying environmental fate of ~3H-labelled compounds. A complete mass balance was obtained over the whole duration with total recoveries ranging from 91.3% to 98.8%. In water, a DT_(50)-value of ivermectin of ＜6 h and a DT_(90)-value of 16.8 d were obtained. The DT_(50)-value of ivermectin in the entire system was 127 d. Maximum distribution coefficients were calculated to K_d = 160 L kg~(-1) and K_(oc) = 3550 L kg~(-1). The fraction of bound residues increased to a maximum percentage of 30.4% after 188 d. In total about 31.3% of the initially applied ivermectin were transformed after 188 d. Two transformation products ivermectin monosaccharide and ivermectin aglycone, could be identified in samples from day 100 and 188, respectively. However, additional peaks which were observed in the radio-chromatograms indicate that several other transformation product are formed.
机译：这项研究调查了〜3H-伊维菌素及其代谢产物在好氧沉积物/水系统中的长期命运。通过液体闪烁计数法测量沉积物和水中的总放射性，并使用放射性高效液相色谱法测定转化产物。装有冷却系统和集水器的测试系统对研究〜3H标记的化合物的环境命运显示出极好的适用性。在整个过程中获得了完整的质量平衡，总回收率为91.3％至98.8％。在水中，伊维菌素的DT_（50）值＜6 h，而DT_（90）值为16.8 d。伊维菌素在整个系统中的DT_（50）值为127 d。计算最大分配系数为K_d = 160 L kg〜（-1）和K_（oc）= 3550 L kg〜（-1）。 188 d后，结合残基的比例增加到最大30.4％。 188 d后，最初应用的伊维菌素总量约占31.3％。在第100天和第188天的样品中分别鉴定出两种转化产物伊维菌素单糖和伊维菌素糖苷配基。但是，在放射色谱图中观察到的其他峰表明形成了其他几种转化产物。

著录项

  • 来源
    《Chemosphere》 |2009年第10期|1321-1325|共5页
  • 作者

    Carsten Prasse; Dirk Loeffler; Thomas A. Ternes;

  • 作者单位

    Federal Institute of Hydrology (BFG), Am Mainzer Tor 1 D-56068 Koblenz, Germany;

    Federal Institute of Hydrology (BFG), Am Mainzer Tor 1 D-56068 Koblenz, Germany;

    Federal Institute of Hydrology (BFG), Am Mainzer Tor 1 D-56068 Koblenz, Germany;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    transformation; long-term fate; radio tracer; ~3H-labelled compound;

    机译：转型;长期的命运无线电示踪剂〜3H标记的化合物;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号