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The impact of elevated blood lead levels in children on maternal health-related quality of life

机译：儿童血铅水平升高对母体健康状生活质量的影响

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Kabwe is a mining town in Zambia that has been ranked among "the ten most polluted places in the world" with previous findings of serious lead (Pb) pollution. In this study, we aim to examine the impact of childhood Pb poisoning on the health-related quality of life (HRQoL) of mothers in Kabwe. The HRQoL was assessed using the Short-Form 36 survey for 404 mothers coming from residences in 40 randomly selected standard enumeration areas (SEAs). Blood lead levels (BLLs) of the household members including the mothers themselves were measured. We found a significant positive correlation between the BLLs of the mothers and their children (R = 0.6385, p 0.0001), while the BLLs of preschool-aged and school-aged children were significantly higher than those of their mothers and fathers. Using the data sets containing the BLLs of the household members, the age of the mothers, the household income, and the household SEA, we performed stepwise multiple linear regression analyses. The results showed significant negative associations between the representative BLL of household children and the BLL of preschool-aged children with the vitality and mental health scores of their mothers. Additionally, the BLL of school-aged children was only significantly associated with the mental health score of their mothers. By contrast, there was a significant negative association between the BLLs of the mothers with the social role functioning score. This suggests that elevated BLLs in children have a negative impact on the mental health conditions of their mothers regardless of the mothers' BLL. (C) 2021 The Author(s). Published by Elsevier Ltd.
机译：Kabwe是赞比亚的矿业镇，该镇被排名在“世界十大最污染的地方”中，以前的认真铅（PB）污染。在这项研究中，我们的目标是探讨儿童时期PB中毒对Kabwe母亲健康有关质量（HRQOL）的影响。利用404名随机选择的标准枚举区域（SEA）的404名母亲的短期调查评估了HRQOL。测量包括母亲自己的家庭成员的血铅水平（BLL）。我们发现母亲和孩子的BLL（r = 0.6385，p＆ 0.0001）之间的显着正相关，而学前班和学龄儿童的BLL显着高于母亲和父亲。使用包含家庭成员的BLL的数据集，母亲的年龄，家庭收入和家庭海，我们逐步进行了多元线性回归分析。结果表明，家庭儿童的代表BLL与学龄前儿童的BLL与其母亲的生命力和心理健康成绩之间存在显着的负面关联。此外，学龄儿童的BLL与母亲的心理健康分数显着相关。相比之下，母亲的BLL与社会角色运作得分之间存在显着的负面关联。这表明儿童的升高的BLL对他们母亲的心理健康状况产生负面影响，而不管母亲的BLL如何。 （c）2021提交人。 elsevier有限公司出版

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