...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chinese science bulletin >Infection of SARS-CoV on juvenile and adult Brandt's vole Microtus brandtii
【24h】

Infection of SARS-CoV on juvenile and adult Brandt's vole Microtus brandtii

机译：SARS冠状病毒对布氏田鼠田鼠和成年田鼠田鼠的感染

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We studied the infectious effect of SARS-CoV virus on juvenile and adult Brandt's Vole (Microtus brandtii) by nasal cavity spraying method (CCID_(50) is 10~(5.7)). SARS virus caused serious deaths in adults. The death adults demonstrated hemorrhage from mouth, nasal cavity and intestine, hemorrhageious interstitial pneumonia and gore in liver, spleen and kidney. The survival adults demonstrated local hemorrhagic spot in lung and emphysema, but the other organs showed no pathological abnormality. SARS virus caused no deaths in juveniles, but locomotion of infected juveniles became slower. In the early stage, there was local pneumonia in lung and SARS viruses were isolated from the pathological tissue. Only one control juvenile lived and the infected juvenile showed local pneumonia in lung. The results demonstrated that SARS-CoV infected Brandt's vole seriously and adults were more susceptive to SARS-CoV than juveniles. The Brandt's vole may be a potential animal model for SARS research.
机译：我们通过鼻腔喷洒法（CCID_（50）为10〜（5.7））研究了SARS-CoV病毒对少年和成年勃氏田鼠的感染作用。 SARS病毒导致成年人严重死亡。死亡成年人表现出口腔，鼻腔和肠道出血，出血性间质性肺炎和肝脏，脾脏和肾脏的出血。存活的成年人表现出在肺和肺气肿中的局部出血点，但是其他器官未显示出病理异常。 SARS病毒未导致少年死亡，但被感染少年的活动速度变慢。在早期，肺中存在局部肺炎，并且从病理组织中分离出SARS病毒。只有一个对照少年活着，被感染的少年在肺部显示局部肺炎。结果表明，SARS-CoV严重感染了Brandt的田鼠，并且成年人比青少年更容易感染SARS-CoV。勃兰特的田鼠可能是SARS研究的潜在动物模型。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号