Cyclic AMP response element binding protein (CREB) par - ticipates in the heat-inducible expression of human hsp90β gene

Liu Bingsheng; Wu Ninghua; Shen Yufei

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Cyclic AMP response element binding protein (CREB) par - ticipates in the heat-inducible expression of human hsp90β gene

机译：环状AMP反应元件结合蛋白（CREB）参与人hsp90β基因的热诱导表达

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Human heat shock protein 90β gene (hsp90β) is a constitutiely expressed heat shock gene existing in most of cell types tested that can be further induced by heat shock. Chloramphenical acetyl transferase (CAT) reporter plasmids Driven by different regulatory fragments of hsp90β gene Were constructed and transfected into Jurkat cells to explore The role of a cAMP response element (CRE) in the upstream Of the gene.

机译：人热休克蛋白90β基因（hsp90β）是组成型表达的热休克基因，存在于大多数测试的细胞类型中，可以通过热休克进一步诱导。构建了由hsp90β基因的不同调控片段驱动的氯代乙酰基乙酰转移酶（CAT）报告质粒，并将其转染到Jurkat细胞中，以探索cAMP反应元件（CRE）在基因上游的作用。

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来源
《Chinese science bulletin》 |2001年第19期|p.1645-1648|共4页
作者
Liu Bingsheng; Wu Ninghua; Shen Yufei;
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正文语种 eng
中图分类自然科学现状及发展;
关键词
hsp90β gene; CRE; CREB;

机译：hsp90β基因;华创;CREB;

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1. Role of basic region leucine zipper transcription factors cyclic AMP response element binding protein (CREB), CREB2, activating transcription factor 2 and CAAT/enhancer binding protein alpha in cyclic AMP response element-mediated transcription. [J] . Thiel G, Al Sarraj J, Vinson C, Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2005,第2期

机译：碱性区域亮氨酸拉链转录因子环状AMP反应元件结合蛋白（CREB），CREB2，活化转录因子2和CAAT /增强子结合蛋白α在环状AMP反应元件介导的转录中的作用。
2. Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2 [J] . Su-Jin Kim, Cuilan Nian, Scott Widenmaier, Molecular and Cellular Biology . 2008,第5期

机译：葡萄糖依赖性促胰岛素多肽介导的β细胞抗凋亡Bcl-2基因表达的上调由环AMP（cAMP）响应元件结合蛋白（CREB）和cAMP响应性CREB共激活因子2协调。
3. TRANSCRIPTIONAL INDUCTION OF THE HUMAN RENIN GENE BY CYCLIC AMP REQUIRES CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN (CREB) AND A FACTOR BINDING A PITUITARY-SPECIFIC TRANS-ACTING FACTOR (PIT-1) MOTIF [J] . Germain S, Konoshita T, Philippe J, The Biochemical Journal . 1996,第0期

机译：循环AMP对人肾素基因的转录诱导需要循环AMP反应元素结合蛋白（CREB）和与垂体特异性交易因子（PIT-1）结合的因子
4. CREB-binding Protein (CBP) p300 Enhanced the Expression of Cardiac Hypertrophy-Specific Genes Activated by Myocardin-Related Transcription Factor-A (MRTF-A) [C] . Li Mingzhe, Wang Zhenyu, Xie Zhongyi, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：CREB结合蛋白（CBP）p300增强心肌相关转录因子-A（MRTF-A）激活的心肌肥大基因的表达。
5. Impairment of cAMP response element binding protein (CREB) signaling in Alzheimer's disease: Implication for neurodegeneration. [D] . He, Yang. 2006

机译：阿尔茨海默氏病中cAMP反应元件结合蛋白（CREB）信号传导的受损：对神经变性的影响。
6. Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP) Response Element Binding Protein (CREB) and cAMP-Responsive CREB Coactivator 2 [O] . Su-Jin Kim, Cuilan Nian, Scott Widenmaier, 2008

机译：葡萄糖依赖性促胰岛素多肽介导的β细胞抗凋亡Bcl-2基因表达的上调由环AMP（cAMP）响应元件结合蛋白（CREB）和cAMP响应性CREB共激活因子2协调。
7. Role of basic region leucine zipper transcription factors cyclic AMP response element binding protein (CREB), CREB2, activating transcription factor 2 and CAAT/enhancer binding protein alpha in cyclic AMP response element-mediated transcription [O] . Gerald Thiel, Jude Al Sarraj, Charles Vinson, 2005

机译：基本区域亮氨酸拉链转录因子的作用循环AMP响应元件结合蛋白（CREB），CREB2，激活转录因子2和Caat / Enhancer结合蛋白α在循环AMP响应元件介导的转录中
8. Activation of Mitogen-Activated Protein Kinases and Cyclic Amp Response Element-Binding Protein in Synaptic Plasticity. [R] . Voulalas, P. J. 1997

机译：突触可塑性中丝裂素活化蛋白激酶和环状放大器反应元件结合蛋白的激活。

Cyclic AMP response element binding protein (CREB) par - ticipates in the heat-inducible expression of human hsp90β gene

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