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Epidemiology of Methicillin-Resistant Staphylococcus aureus

机译：耐甲氧西林金黄色葡萄球菌的流行病学

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摘要

The frequency of methicillin-resistant Staphylococcus aureus (MRSA) infections continues to grow in hospital-associated settings and, more recently, in community settings in the United States and globally. The increase in the incidence of infections due to S. aureus is partially a consequence of advances in patient care and also of the pathogen's ability to adapt to a changing environment. Infection due to S. aureus imposes a high and increasing burden on health care resources. A growing concern is the emergence of MRSA infections in patients with no apparent risk factors. MRSA infection in community settings involves considerable morbidity and mortality, as does nosocomial MRSA infection. For community-associated MRSA, person-to-person transmission has been reported, and several factors have been shown to predict disease. We examine the trends in both nosocomial and community-associated MRSA infections and explore recent studies of the mechanisms that allow S. aureus to become resistant to currently available drugs.
机译：耐甲氧西林金黄色葡萄球菌（MRSA）感染的频率在医院相关环境中以及最近在美国和全球的社区环境中持续增长。金黄色葡萄球菌引起的感染发生率的增加部分是由于患者护理水平的提高以及病原体适应不断变化的环境的能力所致。金黄色葡萄球菌引起的感染给卫生保健资源带来了高且日益增加的负担。没有明显危险因素的患者中，MRSA感染的出现越来越引起人们的关注。社区环境中的MRSA感染与医院内MRSA感染一样，具有较高的发病率和死亡率。对于社区相关的MRSA，已经报道了人与人之间的传播，并且已经显示出多种因素可以预测疾病。我们检查了医院和社区相关的MRSA感染的趋势，并探索了有关机制的最新研究，这些机制使金黄色葡萄球菌对当前可用的药物产生抗药性。

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  • 来源
    《Clinical Infectious Diseases》 |2008年第5期|p.344-349|共6页
  • 作者

    Helen W. Boucher1 and G. Ralph Corey2;

  • 作者单位

    1Division of Infectious Diseases, Tufts University Medical School and New England Medical Center, Boston, Massachussetts 2Division of Infectious Diseases, Duke University Medical School and Duke Clinical Research Institute, Durham, North Carolina;

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