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首页> 外文期刊>Cognitive Neuropsychiatry >The role of premorbid personality and cognitive factors in awareness of illness, memory, and behavioural functioning in Alzheimer's disease
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The role of premorbid personality and cognitive factors in awareness of illness, memory, and behavioural functioning in Alzheimer's disease

机译：病前人格和认知因素在阿尔茨海默病疾病，记忆和行为功能意识中的作用

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Introduction. Research has suggested an association between personality factors and awareness in patients with dementia, yet valid measurement of premorbid personality is problematic. The present study aimed to better reveal the relationship between premorbid personality and awareness by using improved methodology. Moreover, the study aims to contrast the strength of the relationship of premorbid personality and awareness with that of cognitive factors. Methods. Awareness of illness, symptoms, mnemonic and behavioural impairments, and treatment compliance were measured in 27 patients with mild-to-moderate Alzheimer's disease (AD) diagnosed by standard criteria for probable AD. Participant premorbid personality was measured using average retrospective Neuroticism-Extroversion-Openness Inventory (NEO-FFI) scores from two informants. Correlations were performed to investigate the relationship between awareness and personality dimensions, as well as measures of cognitive style, neuropsychological function, mood, carer burden, and sociodemographic factors. Results. There was little relationship between awareness and personality scores, but modest associations between awareness and mood, age, and age of onset of first symptoms. Awareness of memory was related to memory functioning. Increased carer burden was associated with lack of awareness of cognitive-behavioural deficits but there were only few and weak associations between awareness and measures of cognitive functioning. Conclusions. There was little support for an association between previous personality and awareness in dementia. However, increased carer burden was associated specifically with lack of awareness of cognitive-behavioural deficits not deficits in ADL, whereas lower awareness of ADL and not cognitive-behavioural deficits was associated with age. Awareness of memory appeared to be a metamemory capacity. Mood and age rather than personality and cognition are stronger predictors of awareness in early Alzheimer's disease.View full textDownload full textKeywordsAlzheimer's disease, Awareness, Cognition, Dementia, Insight, PersonalityRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/13546805.2011.588007
机译：介绍。研究表明，痴呆患者的人格因素与意识之间存在关联，但对病前人格的有效测量存在问题。本研究旨在通过使用改进的方法更好地揭示病前人格与意识之间的关系。此外，该研究旨在对比病前人格和意识与认知因素之间关系的强度。方法。通过标准的可疑AD标准诊断，对27名轻度至中度阿尔茨海默氏病（AD）患者进行了疾病意识，症状，记忆和行为障碍以及治疗依从性的测量。参加者的病前人格使用来自两名线人的平均回顾性神经质-外向性-开放性量表（NEO-FFI）得分进行测量。进行相关性以调查意识和人格维度之间的关系，以及认知风格，神经心理功能，情绪，护理人员负担和社会人口统计学因素的量度。结果。意识和人格分数之间几乎没有关系，但是意识与情绪，年龄和首次症状发作的年龄之间的适度关联。记忆意识与记忆功能有关。照料者负担增加与缺乏对认知行为缺陷的认识有关，但是意识与认知功能测量之间的联系很少且薄弱。结论。先前的性格与痴呆症意识之间的联系几乎没有得到支持。然而，照顾者负担增加与缺乏对认知行为缺陷的认识而不是与ADL的缺乏有关，而对ADL的较低意识而不是认知行为的缺乏与年龄有关。记忆意识似乎是一种元记忆能力。情绪和年龄而非人格和认知是更容易预测早老性阿尔茨海默氏病的指标。查看全文下载全文关键词citeulike，netvibes，twitter，technorati，美味，linkedin，facebook，stumbleupon，digg，google，更多”，发布：“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/13546805.2011.588007

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