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Editorial

机译:社论

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摘要

While innovation, scientific expertise, business flair and leadership vision clearly are important factors in the success of anpharmaceutical company as it strive to create new medicines, a pharmaceutical company’s most valuable asset may prove to benits compound screening libraries. Maintaining and growing these libraries in order to facilitate timely and effective highnthroughput screening campaigns is a challenging responsibility,nThis challenge generally falls upon “Material Management” or HTS groups and their work is crucial to screening success.nChallenges that “Material Management” or HTS groups must address include determining criteria for deciding whichncompound should be included in the library. Selection can be based on combinatorial chemistry libraries, medicinal chemistrynintermediates, and even natural products extracts, purified natural products, etc…
机译:尽管创新,科学专业知识,业务才能和领导才能显然是制药公司成功开发新药的成功因素,但制药公司最有价值的资产可能证明是化合物筛选库。维护和发展这些图书馆以促进及时有效的高通量筛选活动是一项具有挑战性的责任。n这一挑战通常落在“材料管理”或HTS小组上,他们的工作对筛选成功至关重要。n“材料管理”或HTS小组面临的挑战必须解决的问题包括确定标准,以决定应在库中包括哪种化合物。选择可以基于组合化学文库,药用化学中间体,甚至是天然产物的提取物,纯化的天然产物等。

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