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首页> 外文期刊>IEEE Transactions on Communications >A Communication Theoretical Analysis of Synaptic Multiple-Access Channel in Hippocampal-Cortical Neurons
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A Communication Theoretical Analysis of Synaptic Multiple-Access Channel in Hippocampal-Cortical Neurons

机译:海马皮质神经元突触多路通道的通信理论分析

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Communication between neurons occurs via transmission of neural spike trains through junctional structures, either electrical or chemical synapses, providing connections among nerve terminals. Since neural communication is achieved at synapses, the process of neurotransmission is called synaptic communication. Learning and memory processes are based on the changes in strength and connectivity of neural networks which usually contain multiple synaptic connections. In this paper, we investigate multiple-access neuro-spike communication channel, in which the neural signal, i.e., the action potential, is transmitted through multiple synaptic paths directed to a common postsynaptic neuron terminal. Synaptic transmission is initiated with random vesicle release process from presynaptic neurons to synaptic paths. Each synaptic channel is characterized by its impulse response and the number of available postsynaptic receptors. Here, we model the multiple-access synaptic communication channel, and investigate the information rate per spike at the postsynaptic neuron, and how postsynaptic rate is enhanced compared to single terminal synaptic communication channel. Furthermore, we analyze the synaptic transmission performance by incorporating the role of correlation among presynaptic terminals, and point out the postsynaptic rate improvement.
机译:神经元之间的通讯是通过神经突波列通过连接结构(电或化学突触)的传递而发生的,从而在神经末梢之间提供连接。由于神经通讯是在突触处实现的,因此神经传递的过程称为突触通讯。学习和记忆过程基于神经网络的强度和连通性的变化,神经网络通常包含多个突触连接。在本文中,我们研究了多路访问的神经峰值通信通道,其中的神经信号(即动作电位)通过指向通用突触后神经元末端的多个突触路径传输。从突触前神经元到突触路径的随机小泡释放过程启动了突触传递。每个突触通道的特征在于其冲激反应和可用的突触后受体数量。在这里,我们对多路访问突触通信通道进行建模,并研究突触后神经元每个尖峰的信息速率,以及与单末端突触通信通道相比如何提高突触后速率。此外,我们通过结合突触前终端之间的相关作用来分析突触传递性能,并指出突触后速率的提高。

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