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Effect of structural stiffness of composite bone plate-scaffold assembly on tibial fracture with large fracture gap

机译：复合骨板-支架组合结构刚度对大裂隙胫骨骨折的影响

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In high-energy trauma, severe segmental bone fractures are generally fixed using a combination of a bone plate and a scaffold. In the present study, simulation of the bone healing process of a fractured tibia with a 30 mm fracture gap to which a bone plate-scaffold assembly was applied was performed. A flexible composite bone plate was used to assemble the bone fractures, and a scaffold was inserted in the defected segment. It is well known that the material properties of a bone plate and scaffold affect the healing progress of bone fractures. Therefore, three polymer-based composite materials with different Young's moduli and a few functionally graded materials (FGMs) were used to construct the scaffolds in order to investigate the effect of structural stiffness on the healing process of fractured bones. A mechanoregulation algorithm with a deviatoric strain was programmed in a user subroutine, and iterative calculations were performed using the commercially available finite element code ABAQUS 6.10 to estimate the tissue differentiation process during bone healing. The most appropriate combination of a bone plate and scaffold was proposed for a particular fracture configuration. (C) 2015 Elsevier Ltd. All rights reserved.
机译：在高能创伤中，通常使用骨板和支架的组合固定严重的节段性骨折。在本研究中，模拟了骨折间隙为30 mm的胫骨骨折的愈合过程，并应用了骨板-脚手架组件。使用柔性的复合骨板组装骨折，并将脚手架插入缺损段。众所周知，骨板和支架的材料特性影响骨折的愈合过程。因此，使用三种具有不同杨氏模量的聚合物基复合材料和一些功能梯度材料（FGM）来构建支架，以研究结构刚度对骨折骨骼愈合过程的影响。在用户子例程中编写了具有偏应变的机械协调算法，并使用市售的有限元代码ABAQUS 6.10进行了迭代计算，以估算骨骼愈合过程中的组织分化过程。对于特定的骨折构造，提出了最合适的骨板和支架组合。 （C）2015 Elsevier Ltd.保留所有权利。

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