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首页> 外文期刊>Composite Structures >Characterization of a novel bioactive composite using advanced X-ray computed tomography
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Characterization of a novel bioactive composite using advanced X-ray computed tomography

机译：使用先进的X射线计算机断层扫描技术表征新型生物活性复合材料

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A novel bioactive, porous silica-calcium phosphate nanocomposite (SCPC) that can be used to treat large bone defects in load-bearing positions has been tested and has shown great potential for applications in tissue engineering. Porosity is essential to the performance of the composite material as a tissue engineering scaffold, as porous scaffolds provide a physical, 3-D template to support new tissue formation. However, porosity characterization using conventional techniques such as porosimetry or scanning electron microscopy requires extensive preparation of samples and may destroy important features during preparation and analysis stage. In this work, the new composite is characterized using an advanced high resolution X-ray computed tomography, which is a non-destructive testing technique that allows construction of the 3-D topology of the microstructure. The results clearly show the effectiveness and versatility of this technique in characterizing the porous architecture of the novel composite biomaterial. The pore distribution, morphology and inter-connectivity in the composite scaffolds were found to be ideal for use in tissue engineering applications.
机译：一种新型的生物活性，多孔二氧化硅-磷酸钙纳米复合材料（SCPC）可用于治疗承重部位的大骨缺损，并且已经在组织工程中显示出巨大的潜力。多孔性对于复合材料作为组织工程支架的性能至关重要，因为多孔支架提供了物理的3-D模板来支持新的组织形成。但是，使用常规技术（例如孔隙率法或扫描电子显微镜）表征孔隙度需要大量准备样品，并且可能会在制备和分析阶段破坏重要特征。在这项工作中，新的复合材料使用先进的高分辨率X射线计算机断层扫描进行表征，这是一种无损测试技术，可以构建微结构的3-D拓扑结构。结果清楚地表明了该技术在表征新型复合生物材料的多孔结构方面的有效性和多功能性。发现复合支架中的孔分布，形态和相互连接性非常适用于组织工程应用。

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