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Optical trapping-assisted SERS platform for chemical and biosensing applications: Design perspectives

机译：用于化学和生物传感应用的光阱辅助SERS平台：设计观点

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摘要

Useful approaches to tackle Brownian motion of microanoparticles and overcome the poor reproducibility of surface-enhanced Raman scattering (SERS) events are highly desirable, especially for performing SERS sensing in ultra-low concentration of analytes. When integrated with the SERS measurement system, optical trapping is a versatile approach for manipulating particles and thereby improving the SERS performance. A review of the recent research advancements in optical trapping-assisted SERS platform can provide critical inputs for optimizing SERS-based sensing methods for real-life applications. In this paper, we present an in-depth review on the systematic classification of optical trapping-assisted (e.g., far-field and near-field optical tweezers) SERS sensing platform and discuss its latest practical applications in biosensing, bioimaging, chemical monitoring, particle manipulation, single cell analysis, etc. Also, we summarize some important strategies to suppress the plasmonic heating effect which hinders the stability of optical tweezers. Furthermore, we also propose non-optical trapping approaches for manipulating nanoparticles/molecules that are promising for prospective SERS sensing. For example, plasmonic heating is not completely deleterious to particle manipulation. Particularly, plasmonenhanced thermophoresis technique is a useful non-optical approach for trapping particles/molecules and incorporating with SERS detection. Finally, we conclude with future perspectives for designing the new generation of optical tweezers. (C) 2017 Elsevier B. V. All rights reserved.
机译：非常需要有用的方法来解决微米/纳米粒子的布朗运动并克服表面增强拉曼散射（SERS）事件的低重现性，尤其是对于在超低浓度的分析物中进行SERS传感的情况。当与SERS测量系统集成在一起时，光阱技术是一种用于操纵粒子从而提高SERS性能的通用方法。对光陷陷辅助SERS平台的最新研究进展的回顾可以为优化基于SERS的现实生活中的传感方法提供关键输入。在本文中，我们对光捕获辅助（例如，远场和近场光镊）SERS传感平台的系统分类进行了深入的综述，并讨论了其在生物传感，生物成像，化学监测，粒子操纵，单细胞分析等。此外，我们总结了一些重要的策略来抑制等离子体加热效应，这种效应阻碍了光镊的稳定性。此外，我们还提出了用于操纵纳米粒子/分子的非光学捕获方法，这些方法有望用于预期的SERS传感。例如，等离子加热并不完全有害于粒子操纵。特别地，等离激元增强热泳技术是一种有用的非光学方法，用于捕获颗粒/分子并结合SERS检测。最后，我们总结了设计新一代光学镊子的未来前景。 （C）2017 Elsevier B.V.保留所有权利。

著录项

  • 来源
    《Coordination chemistry reviews》 |2017年第5期|138-152|共15页
  • 作者

    Yuan Yufeng; Lin Yining; Gu Bobo; Panwar Nishtha; Tjin Swee Chuan; Song Jun; Qu Junle; Yong Ken-Tye;

  • 作者单位

    Shenzhen Univ, Coll Optoelect Engn, Minist Educ & Guangdong Prov, Key Lab Optoelect Devices & Syst, Shenzhen 518060, Peoples R China|CNRS, NTU, THALES, CINTRA,UMI 3288, Res Techno Plaza,50 Nanyang Dr,Border X Block, Singapore 637553, Singapore;

    Shenzhen Univ, Coll Optoelect Engn, Minist Educ & Guangdong Prov, Key Lab Optoelect Devices & Syst, Shenzhen 518060, Peoples R China;

    Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore;

    Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore;

    Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore;

    Shenzhen Univ, Coll Optoelect Engn, Minist Educ & Guangdong Prov, Key Lab Optoelect Devices & Syst, Shenzhen 518060, Peoples R China;

    Shenzhen Univ, Coll Optoelect Engn, Minist Educ & Guangdong Prov, Key Lab Optoelect Devices & Syst, Shenzhen 518060, Peoples R China;

    Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore|CNRS, NTU, THALES, CINTRA,UMI 3288, Res Techno Plaza,50 Nanyang Dr,Border X Block, Singapore 637553, Singapore;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    SERS; Far-field optical trapping-based SERS; Near-field optical trapping-based SERS; Plasmonic heating effect; Optical tweezers;

    机译：SERS;基于远场光阱的SERS;基于近场光阱的SERS;等离子体加热效应;光镊;

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