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Template synthesis of azacyclam metal complexes using primary amides as locking fragments

机译:使用伯酰胺作为锁定片段的阿扎环素金属配合物模板合成

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Nickel(Ⅱ) and copper(Ⅱ) azacyclam complexes can be obtained through a metal template procedure involving the pertinent open-chain tetramine, formaldehyde and a primary amide (either carboxy- or sul-fonamide) as a locking fragment. Azacyclam complexes, which display the same properties and solution behavior of the corresponding cyclam analogues, can be obtained with any desired side-chain appended to the ligand's framework, by choosing the appropriate amide derivative, through a convenient one-pot synthesis. This opens the way to the design of multi centered redox systems, redox switches of fluorescence, and anion receptors of unusually high Bronsted acidity.
机译:镍(Ⅱ)和铜(Ⅱ)的氮杂环磷酰胺配合物可通过金属模板方法获得,该方法涉及相关的开链四胺,甲醛和伯酰胺(羧基或磺酰胺)作为锁定片段。通过选择合适的酰胺衍生物,通过方便的一锅合成,可以在配体骨架上附加任何所需侧链的情况下,获得与相应的cyclam类似物具有相同特性和溶液行为的Azacyclam复合物。这为设计多中心氧化还原系统,荧光的氧化还原开关和异常布朗斯台德酸度的阴离子受体打开了道路。

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