+276G>T Single Nucleotide Polymorphism in the Adiponectine (APM1) Gene in Donors from the Kharkiv Population

L.A.Atramentova; V.V.Poltorak; T.V.Tyzhnenko; M.Yu.Gorshunskaya; A.R.Pochernyaev

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+276G>T Single Nucleotide Polymorphism in the Adiponectine (APM1) Gene in Donors from the Kharkiv Population

机译：哈尔科夫人群供体脂联素（APM1）基因中+ 276G> T单核苷酸多态性

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+276G> T polymorphism in the adiponectine gene (APM1) was studied in 103 samples obtained from donors in the Kharkiv population (men/women: 64/38; 70 Ukrainian, 33 Russian). The T- and G-allele frequencies did not significantly differ between either men and women or between Russians and Ukrainians and comprised P_T = 0.55 and P_G = 0.45 in the general group. The genotype distribution deviated from the Hardy-Weinberg equilibrium: the heterozygote frequency was 1.55 times higher compared to the selectively neutral value, while the TT- and GG-homozygote frequencies were 0.55 and 0.33 of the equilibrium value, respectively.

机译：在从哈尔科夫人口的供体中获得的103个样本中，脂联素基因（APM1）中的+ 276G> T多态性得到了研究（男性/女性：64/38； 70乌克兰人，33俄罗斯人）。男女之间或俄罗斯人和乌克兰人之间的T-和G-等位基因频率无显着差异，一般人群中P_T = 0.55，P_G = 0.45。基因型分布偏离Hardy-Weinberg平衡：杂合子频率是选择性中性值的1.55倍，而TT-和GG-纯合子频率分别是平衡值的0.55和0.33。

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《Cytology and genetics》 |2010年第6期|p.361-364|共4页
作者
L.A.Atramentova; V.V.Poltorak; T.V.Tyzhnenko; M.Yu.Gorshunskaya; A.R.Pochernyaev;
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Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Sciences, Kharkiv;

Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Sciences, Kharkiv;

Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Sciences, Kharkiv;

Kharkiv Medical Academy of Postgraduate Education;

Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Sciences, Kharkiv;

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+276G>T Single Nucleotide Polymorphism in the Adiponectine (APM1) Gene in Donors from the Kharkiv Population

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