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首页> 外文期刊>Cytology and genetics >COLOR-CHANGING BALSAMS IN THE CONTEXT OF GRADUAL TESTING OF THEIR POTENTIAL MUTAGENIC EFFECT ON GENETICALLY VARIABLE MICROORGANISMS
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COLOR-CHANGING BALSAMS IN THE CONTEXT OF GRADUAL TESTING OF THEIR POTENTIAL MUTAGENIC EFFECT ON GENETICALLY VARIABLE MICROORGANISMS

机译：在对潜在的突变对遗传变异的微生物的作用进行常规测试的背景下，变色的香脂

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摘要

The potential mutagenic activity of 17 color-changing balsams that are used as cosmetic agents for temporary hair dyeing is studied by means of the Ames semiquantitative technique with metabolic activation of the post-mitochondrial fraction of rat liver homogenate preprocessed by means of sodium phenobarbital (to induce monooxygenase of mixed function). The balsams included aqueous solutions of dyes and pigments that are mixed on the hair surface when used. Such hair dyes may be removed by a single effective washing of the hair with a shampoo. The presence of potential mutagenic activity in almost all of the color-changing balsams is demonstrated. Three agents - red tree, chestnut, and ebony - are shown to be the most active inducers of genetic mutations, all of these balsams demonstrating an effect of "average" strength in terms of our classification. One of the color-changing balsams, burgundy, is shown to be genetically neutral. Other preparations demonstrate a mutagenic effect of "weak" strength with five-to two-fold exceedance of the control values.
机译：通过Ames半定量技术，通过苯巴比妥钠预处理的大鼠肝匀浆线粒体后部分的代谢活化，研究了Ames半定量技术研究了用作临时染发美容剂的17种变色香脂的潜在诱变活性。诱导混合功能的单加氧酶）。香脂包括当使用时在头发表面上混合的染料和颜料的水溶液。可以通过用洗发剂对头发进行单次有效洗涤来除去这种染发剂。几乎所有的变色香脂中都存在潜在的诱变活性。三种药剂-红树，栗子和乌木-被证明是最活跃的遗传突变诱导剂，所有这些香脂在我们的分类中均显示出“平均”强度的作用。变色的香脂之一，勃艮第被证明在遗传上是中性的。其他制剂显示出“弱”强度的诱变作用，超出对照值五到两倍。

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