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首页> 外文期刊>Cytology and genetics >The Linkage of Polymorphic Variants of Genes Gh, Prl, and Pit-1 and Milk Productivity of Cows with Morphology of Cumulus-Oocyte Complex Sampled Post Mortem
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The Linkage of Polymorphic Variants of Genes Gh, Prl, and Pit-1 and Milk Productivity of Cows with Morphology of Cumulus-Oocyte Complex Sampled Post Mortem

机译：基因GH，PRL和PIT-1的多态性变体的连杆，母牛的牛奶生产率与豇豆卵母细胞复合后验尸形态

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摘要

In recent years, the aim of dairy cattle breeding was to increase milk productivity traits. However, there is an observed decrease of fertility traits of cows, and, as a result, early culling of animals. This is due to the fact that causes of decreased reproduction are sometimes impossible to determine and its signs are difficult to estimate. One of the causes for decreasing fertility of cows is the decline in the quality of oocytes capable of fertilization. Therefore, a study into the ratio between the number and quality of oocytes capable of fertilization and the level of milk productivity in cows, as well as association with polymorphic variants of the GH, PRL, and Pit-1 genes, is of scientific interest. The aim of this study was to determine the dependence of the quality and quantity of cow COC obtained post mortem on the level of milk productivity and genetic profile for the genes GH, PRL, and Pit-1. There was high frequency of allele L of the GH gene, 0.942; allele A of the PRL gene, 0.889; and allele B of the Pit-1 gene, 0.710. High average content of COC per ovary was obtained in a group of animals with LL genotype of the GH gene (LL to LV +7.54 units, p = 0.05), and a significant portion of them were viable (LL to LV +4.5 units, p = 0.05). In individuals with the AA genotype of the PRL gene, the average number of isolated viable COC per ovary was higher than in those with the AB genotype (+4.84 units, p = 0.05). Analysis of the association of polymorphic variants of the Pit-1 gene with the quantity and quality of COC did not reveal significant differences in the studied group of individuals. Assessment for the relationship of polymorphic variants of the studied genes with the breeding value (BV) indices of milk productivity, milk fat, and protein content showed that only animals with the LV genotype exceeded their peers with the LL genotype of the GH gene in milk fat and protein content by 8.3 kg (p = 0.05) and 6.0 kg (p = 0.01), respectively. Average calculated breeding value based on quantity of COC of individuals in the studied groups revealed no significant difference.
机译：近年来，乳制品养殖的目的是提高牛奶生产力性状。然而，奶牛的生育性状减少观察到，因此，早期剔除动物。这是由于繁殖减少的原因有时不可能确定，并且其迹象很难估计。减少奶牛生育能力的原因之一是能够受精的卵母细胞质量下降。因此，研究能够受精的卵母细胞的数量和质量与奶牛的牛奶生产率水平的研究以及GH，PRL和PIT-1基因的多态性变体的关系是科学兴趣。本研究的目的是确定牛COC的质量和数量获得验尸对GH，PRL和PIT-1基因生产率和遗传谱的水平的依赖性。 GH基因的等位基因L频率为0.942;等位基因A的PRL基因，0.889;和坑1基因的等位基因B，0.710。在一组具有GH基因的动物（L1至LV + 7.54单位，P <= 0.05）的一组动物中获得了每卵巢的高平均含量，并且它们的大部分是可行的（LL至LV + 4.5单位，p <= 0.05）。在具有PRL基因的AA基因型的个体中，每卵巢的平均分离的可加入COC的数量高于AB基因型（+ 4.84单元，P <= 0.05）。分析坑-1基因的多态性变体与氟碳化合物数量和质量的分析并未揭示学习群体的显着差异。评估研究基因的多态变体与奶粉饲养，牛奶脂肪和蛋白质含量的指标的关系表明，只有具有LV基因型的动物只超过了牛奶中GH基因的LL基因型的同龄蛋白酶脂肪和蛋白质含量分别为8.3千克（p <= 0.05）和6.0kg（p <= 0.01）。基于研究组中的个体的COC的平均计算育种值显示出没有显着差异。

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