• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BioResearch open access. >Determination of Cutoff Values for DEXA-Based Body Composition Measurements for Determining Metabolic and Cardiovascular Health
【24h】

Determination of Cutoff Values for DEXA-Based Body Composition Measurements for Determining Metabolic and Cardiovascular Health

机译：确定基于DEXA的人体成分测量的临界值，以确定代谢和心血管健康

获取原文
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The two components of the body weight (i.e., fat mass and muscle mass) appeared to be of high interest to consider in predicting metabolic health related risks. We aimed to determine cutoff values for fat mass index (FMI) and muscle mass index (MMI), FM/MM, and BMI for metabolic and cardiovascular health. This study was a cross-sectional analysis study conducted in a center of preventive medicine. It included 616 consecutive outpatients: mean age was 56.0±10.0 years (74.6% aged ≥50), and 61.4% were female. Fat and muscle mass were obtained with dual energy X-ray absorptiometry scan analyses. Metabolically unhealthy individuals were defined as people with biological features of dyslipidemia, hyperuricemia, diabetes, and/or hepatitis steatosis. Documented hypertension and/or atherosclerosis of at least one major artery defined individuals with cardiovascular complications. Receiver-operating characteristic curve analysis revealed that the cutoff values for MMI, FMI, and FM/MM were respectively 18.8kg/m2 (sensitivity [Se]=58%; specificity [Sp]=59%), 5.5kg/m2 (Se=61%; Sp=62%), and 0.31 (Se=62%; Sp=62%) in men; and 14.1kg/m2 (Se=52%; Sp=54%), 5.5kg/m2 (Se=65%; Sp=67%), 0.39 (Se=73%; Sp=73%) in women for predicting metabolic health. Values were 19.3kg/m2 (Se=58%; Sp=59%), 7.0kg/m2 (Se=61%; Sp=62%) and 0.49 (Se=62%; Sp=62%) in men; and 15.7kg/m2 (Se=58%; Sp=59%), 6.4kg/m2 (Se=61%; Sp=62%) and 0.35 (Se=62%; Sp=62%) in women for cardiovascular complications. Whatever the outcomes considered, the Youden indexes for BMI values were systematically below 25?kg/m2, except for cardiovascular complications in men, where the threshold for the best Se/Sp was 25.7?kg/m2. These cutoff values for FMI, MMI, and FM/MM could be of practical value for the clinical evaluation of a deficit in MM with or without excess of FM. They complement the classical concept of BMI in a more qualitative manner and extend the analysis of its impact on health outcomes to all BMI categories.
机译：在预测与代谢健康有关的风险时，体重的两个组成部分（即脂肪和肌肉）似乎引起了极大的兴趣。我们旨在确定脂肪质量指数（FMI）和肌肉质量指数（MMI），FM / MM和BMI的代谢和心血管健康的临界值。这项研究是在预防医学中心进行的横断面分析研究。它包括616名连续的门诊患者：平均年龄为56.0±10.0岁（74.6％≥50岁），女性为61.4％。脂肪和肌肉质量是通过双能X射线骨密度仪扫描分析获得的。代谢不健康的个体被定义为具有血脂异常，高尿酸血症，糖尿病和/或肝炎脂肪变性的生物学特征的人。记录的至少一条大动脉的高血压和/或动脉粥样硬化定义为患有心血管并发症的个体。接收者操作特征曲线分析显示，MMI，FMI和FM / MM的临界值分别为18.8kg / m 2 （灵敏度[Se] = 58％;特异性[Sp] = 59％ ），男性5.5kg / m 2 （Se = 61％; Sp = 62％）和0.31（Se = 62％; Sp = 62％）;和14.1kg / m 2 （Se = 52％; Sp = 54％），5.5kg / m 2 （Se = 65％; Sp = 67％），0.39 （Se = 73％; Sp = 73％）用于预测代谢健康的女性。值分别为19.3kg / m 2 （Se = 58％; Sp = 59％），7.0kg / m 2 （Se = 61％; Sp = 62％）和男性0.49（Se = 62％; Sp = 62％）;和15.7kg / m 2 （Se = 58％; Sp = 59％），6.4kg / m 2 （Se = 61％; Sp = 62％）和0.35女性心血管并发症的发生率（Se = 62％; Sp = 62％）。无论考虑哪种结果，除了男性的心血管并发症（最佳Se / Sp的阈值为25.7？kg / m）外，Youden指数BMI值都一直低于25？kg / m 2 。 2 。 FMI，MMI和FM / MM的这些临界值对于有或没有FM过多的MM缺陷的临床评估可能具有实用价值。他们以更定性的方式补充了BMI的经典概念，并将其对健康结果影响的分析扩展到所有BMI类别。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号