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首页> 外文期刊>BioResearch open access. >Combination of Treatments With or Without Surgery in Localized Provoked Vulvodynia: Outcomes After Three Years of Follow-Up
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Combination of Treatments With or Without Surgery in Localized Provoked Vulvodynia: Outcomes After Three Years of Follow-Up

机译：局部诱发性外阴痛的有或无手术治疗的组合：三年随访后的结果

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Most vulvodynia patients receive combinations of several treatment modalities for their chronic painful condition. If conservative treatments fail, vestibulectomy is considered to be the ultimate treatment option for localized provoked vulvodynia (LPV). The aim of this descriptive study was to analyze relief of pain, quality of life (QoL), and complications associated with combining surgery with conservative treatments among LPV patients, both in short term and after 3 years of follow-up. The study population consisted of a retrospective patient cohort of surgically ( n =?16) and only conservatively ( n =?50) treated LPV patients. QoL data were assessed by a validated questionnaire (RAND-36). Data were collected by reviewing patient records and by aid of postal questionnaires. Efficacy of treatments in relief of pain was measured by numerical rating scale (NRS). Two months after surgery, the NRS scores assessed by a physician were lower in the surgery group than in patients treated only conservatively ( p =?0.008). However, after a median of 36 months of follow-up, self-reported NRS scores and QoL showed no difference between the two patient cohorts. Complication rate after vestibulectomy was 18.8%. The findings suggest that combining surgery with conservative treatments may result in a more effective short-term reduction of pain. However, the effect seemed to be only temporary, as no long-term benefit was achieved.
机译：大多数外阴痛患者因其慢性疼痛状况而接受多种治疗方式的组合。如果保守治疗失败，则前庭切除术被认为是局部诱发性外阴痛（LPV）的最终治疗选择。这项描述性研究的目的是分析LPV患者在短期内和三年随访后的疼痛缓解，生活质量（QoL）以及与手术与保守治疗相结合的并发症。该研究人群由回顾性队列手术患者（n = 16）和仅保守治疗（n = 50）的LPV患者组成。 QoL数据通过经过验证的问卷（RAND-36）进行评估。通过回顾患者记录并借助邮政调查表收集数据。通过数字评分量表（NRS）测量治疗缓解疼痛的功效。手术后两个月，由医生评估的NRS得分在手术组中低于仅接受保守治疗的患者（p =？0.008）。但是，在进行了36个月的中位随访之后，两个患者队列之间的自我报告NRS得分和QoL均无差异。前庭切除术后并发症发生率为18.8％。研究结果表明，手术与保守治疗相结合可能会在短期内更有效地减轻疼痛。但是，这种效果似乎只是暂时的，因为没有实现长期利益。

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