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The ventro-medial prefrontal cortex: a major link between the autonomic nervous system, regulation of emotion, and stress reactivity?

机译:腹内侧前额叶皮层:自主神经系统,情绪调节和应激反应之间的主要联系?

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Recent progress in neuroscience revealed diverse regions of the CNS which moderate autonomic and affective responses. The ventro-medial prefrontal cortex (vmPFC) plays a key role in these regulations. There is evidence that vmPFC activity is associated with cardiovascular changes during a motor task that are mediated by parasympathetic activity. Moreover, vmPFC activity makes important contributions to regulations of affective and stressful situations. This review selectively summarizes literature in which vmPFC activation was studied in healthy subjects as well as in patients with affective disorders. The reviewed literature suggests that vmPFC activity plays a pivotal role in biopsychosocial processes of disease. Activity in the vmPFC might link affective disorders, stressful environmental conditions, and immune function.
机译:神经科学方面的最新进展表明,中枢神经系统的各个区域均具有适度的自主和情感反应。腹内侧前额叶皮层(vmPFC)在这些法规中起着关键作用。有证据表明,vmPFC活性与副交感神经活动介导的运动任务期间的心血管变化有关。此外,vmPFC活动对情绪和压力状况的调节做出了重要贡献。这篇综述选择性地总结了在健康受试者以及情感障碍患者中研究vmPFC激活的文献。综述文献表明,vmPFC活性在疾病的生物社会心理过程中起着关键作用。 vmPFC中的活动可能将情感障碍,压力环境条件和免疫功能联系在一起。

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