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首页> 外文期刊>BMC Ear, Nose and Throat Disorders >Childhood infections, but not early life growth, influence hearing in the Newcastle thousand families birth cohort at age 14?years
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Childhood infections, but not early life growth, influence hearing in the Newcastle thousand families birth cohort at age 14?years

机译：童年期感染，但并非早期生命的增长，会影响纽卡斯尔千户14岁以下出生队列的听力

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Background While current research priorities include investigations of age-related hearing loss, there are concerns regarding effects on childhood hearing, for example through increased personal headphone use. By utilising historical data, it is possible to assess what factors may have increased hearing problems in children in the past, and this may be used to inform current public health policies to protect children against hearing loss and in turn reduce the long-term burden on individuals and services that may possible evolve. The aim of this study was to investigate which factors in early life significantly impacted on hearing level in childhood using existing data from the Newcastle Thousand Families Study, a 1947 birth cohort. Methods Data on early life factors, including growth, socio-economic status and illness, and hearing at age 14?years were collated for a representative subset of individuals from the cohort (n?=?147). Factors were assessed using linear regression analysis to identify associations with hearing thresholds. Results Males were found to have lower hearing thresholds at 250?Hz, 500?Hz and 1?kHz. Main analyses showed no associations between hearing thresholds and early life growth or socio-economic indicators. An increasing number of ear infections from birth to age 13?years was associated with hearing thresholds at 250Hz (p?=?0.04) and 500Hz (p?=?0.03), which remained true for females (p?=?0.050), but not males (p?=?0.213) in sex-specific analysis. Scarlet fever and bronchitis were associated with hearing thresholds at 8?kHz. After adjustment for all significant predictors at each frequency, results remained unchanged. Conclusions We found no associations between childhood hearing thresholds and early life growth and socio-economic status. Consistent with other studies, we found associations between childhood infections and hearing thresholds. Current public health strategies aimed at reducing childhood infections may also have a beneficial effect upon childhood hearing.
机译：背景技术虽然当前的研究重点包括对与年龄有关的听力损失的调查，但人们对儿童听力的影响存在担忧，例如通过增加个人耳机的使用。通过利用历史数据，可以评估过去哪些因素可能增加了儿童的听力问题，并且可以将这些因素用于告知当前的公共卫生政策，以保护儿童免受听力损失，进而减轻儿童的长期负担。可能会发展的个人和服务。这项研究的目的是使用1947年出生队列的新堡千户研究的现有数据，调查早期生活中的哪些因素显着影响了儿童的听力水平。方法对队列中代表性个体的子集（n = 147），收集有关早期生活因素的数据，包括生长，社会经济状况和疾病以及14岁时的听力。使用线性回归分析评估因素，以识别与听力阈值的关联。结果发现男性在250？Hz，500？Hz和1？kHz处的听力阈值较低。主要分析显示，听力阈值与早期生活成长或社会经济指标之间没有关联。从出生到13岁年龄段，耳部感染的增加与250Hz（p？=？0.04）和500Hz（p？=？0.03）的听力阈值有关，女性的听力阈值仍然适用（p？=？0.050），而按性别进行的分析则不包括男性（p？=？0.213）。猩红热和支气管炎与8？kHz的听力阈值有关。在每个频率下对所有重要预测变量进行调整后，结果保持不变。结论我们发现儿童听力阈值与早期生活增长和社会经济地位之间没有关联。与其他研究一致，我们发现儿童期感染与听力阈值之间存在关联。当前旨在减少儿童期感染的公共卫生策略也可能对儿童的听力产生有益的影响。

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