• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Ear, Nose and Throat Disorders >Antimicrobial susceptibility patterns of bacteria isolated from patients with ear discharge in Jimma Town, Southwest, Ethiopia
【24h】

Antimicrobial susceptibility patterns of bacteria isolated from patients with ear discharge in Jimma Town, Southwest, Ethiopia

机译：埃塞俄比亚西南部吉马镇从耳分泌物患者中分离出的细菌的抗菌药敏模式

获取原文
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Otitis media is among the leading causes of childhood illnesses although it can also affect the adults resulting in frequent physician visits, drug prescription and a key contributor to antibiotic resistance. The aim of this study was to determine the risk factors, bacterial profile, and the antimicrobial susceptibility pattern of the isolates from patients with discharging ears which clinically equates to draining otitis media in developing countries with limited medical resources such as otoscope. A prospective cross-sectional study was conducted on 173 patients with draining otitis media. The ear discharge specimens were collected and analyzed by standard microbial techniques. The antibiotic susceptibility profiles were determined for 19 different antibiotics by the standard disk diffusion method. Data was analyzed by SPSS version 22 and the P value of less than 0.05 was considered as statistically significant. Among 173 otitis media patients participated in the study; majority, 102(63%) were pediatrics, out of which 72 (41.61%) were in the age group of less than 4?years. Ear infection was bilateral in 39?(22.54%) and chronic in 100 (57.8%) of the patients. Pathogens were isolated from 160 (92.5%) of the patients with a total of 179 isolates. The predominant isolate was Staphylococcus aureus (30.72%) followed by Proteus spp. (17.89%). The result of this study showed that adult age (p?=?0.031), rural residence (p?=?0.005), previous history of health care visit and treatment (p?=?0.000), upper respiratory tract infection (p?=?0.018) and presence of cigarette smoker in the house (p?=?0.022) had statistically significant association with chronic otitis media. Most of the isolated bacteria showed high level of resistance to ampicillin/amoxicillin (88.3%), penicillin G (79.5%) followed by trimethoprim /sulfamethoxazole (73.8%). Conversely, the majority of bacterial isolates showed moderate susceptibility to ciprofloxacin (72.9%), gentamicin (70.4%), and amikacin (69.3%). Bacterial isolates identified in this study showed trend of multiple drug resistance, majority (67%) being resistant to three or more antimicrobials. Majority of the bacterial isolates were multidrug resistant, hence, efforts to isolate microorganisms and determine the susceptibility pattern should be strengthened to improve the treatment outcome of otitis media instead of the usual trend of empirical treatment.
机译：中耳炎是儿童疾病的主要诱因之一，尽管它也可能影响成年人，导致频繁的就诊，药物处方以及对抗生素耐药性的关键因素。这项研究的目的是确定危险因素，细菌特征和耳分泌物患者分离株的抗菌药敏模式，这在临床上等同于在医疗资源有限的国家（如耳镜）引流中耳炎。对173例引流性中耳炎患者进行了前瞻性横断面研究。收集耳放样本并通过标准微生物技术进行分析。通过标准圆盘扩散法确定了19种不同抗生素的抗生素敏感性分布。数据由SPSS 22版进行分析，P值小于0.05被认为具有统计学意义。在173名中耳炎患者中参加了该研究。大多数儿童为102（63％），其中年龄在4岁以下的儿童为72（41.61％）。耳部感染是双侧39？（22.54％），慢性是100（57.8％）例。从160例（92.5％）患者中分离出病原体，共179株。主要的分离株是金黄色葡萄球菌（30.72％），其次是变形杆菌属。 （17.89％）。这项研究的结果表明，成年年龄（p = 0.031），农村居民（p = 0.005），以前的医疗保健就诊和治疗史（p = 0.000），上呼吸道感染（p？= 0.000）。 ≥0.018）和在家中有吸烟者（p≥0.022）在统计学上与慢性中耳炎相关。大多数分离出的细菌对氨苄青霉素/阿莫西林（88.3％），青霉素G（79.5％），甲氧苄啶/磺胺甲恶唑（73.8％）的耐药性较高。相反，大多数细菌分离株对环丙沙星（72.9％），庆大霉素（70.4％）和阿米卡星（69.3％）表现出中等敏感性。在这项研究中鉴定出的细菌分离株显示出多种耐药性的趋势，大多数（67％）对三种或更多种抗菌药具有耐药性。大多数细菌分离株具有多重耐药性，因此，应加强分离微生物和确定药敏模式的努力，以改善中耳炎的治疗效果，而不是通常的经验治疗趋势。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号