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A Review on Biodegradation of Polymers

机译:聚合物的生物降解研究进展

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The expression "polymer" gets from the antiquated Greek word polus, signifying "some, much" and meros, signifying "parts", and alludes to an atom whose structure is made out of various rehashing units. A polymer is an extensive particle (macromolecules) made out of numerous rehashed subunits, known as monomers. Biodegradable polymers are characterized as polymers included monomers connected to each other through practical gatherings and have unsteady connections in the spine. Polymer corruption is an adjustment in the properties – elasticity, shading, shape, and so forth of a polymer or polymer based item affected by one or more natural components, for example, warmth, light or chemicals. Compound or enzymatic corruption is intervened by water, catalysts, microorganisms. Grouping of biodegradable polymers taking into account the source like natural biodegradable polymers and synthetic biodegradable polymers. Biodegradable polymers have demonstrated their potential for the improvement of new, progressed and proficient DDS and equipped for conveying an extensive variety of bioactive materials. However, just few have entered the business sector since numerous medications confronts the issue of affectability to warmth, shear strengths and association between polymers. These issues can be overcome by completely understanding the debasement component to modify the discharge profile. Numerous engineered biodegradable polymers are accessible and as yet being produced for supported and focused on medication conveyance applications.
机译:“聚合物”一词来自过时的希腊词polus,表示“很多”和“ melos”,表示“部分”,并暗示其原子由各种重整单元组成的原子。聚合物是由许多重整的亚基(称为单体)制成的粗大颗粒(大分子)。可生物降解的聚合物的特征在于包含通过实际聚集彼此连接的单体的聚合物,并且在脊柱中具有不稳定的连接。聚合物破坏是对受一种或多种天然成分(例如,保暖性,光性或化学药品)影响的聚合物或基于聚合物的物品的属性-弹性,阴影,形状等的调整。水,催化剂,微生物会干扰化合物或酶的破坏。考虑到诸如天然可生物降解的聚合物和合成可生物降解的聚合物的来源,对可生物降解的聚合物进行分组。可生物降解的聚合物已经证明了其在改进新的,先进的和熟练的DDS方面的潜力,并且可以输送多种生物活性材料。然而,由于众多药物面临着对温度的影响,剪切强度以及聚合物之间的缔合的问题,因此进入商业领域的很少。这些问题可以通过完全了解变质成分来修改排放曲线来解决。许多可工程改造的可生物降解的聚合物都可以使用,并且已经被生产出来用于支持和专注于药物输送应用。

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