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首页> 外文期刊>BioTechnology: An Indian Journal >Electromagnetic fields low levels altered the DNA infrared region in RA-differentiated SH-SY5Y neuroblastoma cells
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Electromagnetic fields low levels altered the DNA infrared region in RA-differentiated SH-SY5Y neuroblastoma cells

机译:低水平的电磁场改变了RA分化的SH-SY5Y神经母细胞瘤细胞的DNA红外区域

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Differentiated neuroblastoma cells (SH-SY5Y) were used to study the effects of lowstatic magnetic fields (SMFs) and extremely low frequency electromagnetic fields (ELF-EMFs) on the structure of DNA. Fourier Transform Infrared (FTIR) spectroscopy analysis showed that exposures to a SMF at 2mT and to a 50Hz EMF at 0.7mT produced peak???s centroid shift and significant decreases of the phosphate absorption bands in the infrared region of DNA. The exposure also induced significant increase in reactive oxygen species (ROS) production in comparison to control confirming this scenario.
机译:分化神经母细胞瘤细胞(SH-SY5Y)用于研究低静态磁场(SMF)和极低频电磁场(ELF-EMF)对DNA结构的影响。傅立叶变换红外(FTIR)光谱分析表明,暴露于2mT的SMF和0.7mT的50Hz EMF会产生峰质心位移,并显着降低DNA红外区中的磷酸盐吸收带。与确认该情况的对照相比,该暴露还引起了活性氧(ROS)产量的显着增加。

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