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The association between intraocular pressure and different combination of metabolic syndrome components

机译：眼内压与代谢综合征成分不同组合之间的关系

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Background Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the intraocular pressure and metabolic syndrome components with their different combinations. Methods Thirty-one thousand two hundred seventy one healthy people aged 19–79 who attended a community hospital for a health check-up between January 2011 and December 2013 were enrolled in the study. Subjects with a history of intraocular disease, at least in one eye and those receiving medical treatment for glaucoma were excluded. Metabolic syndrome was diagnosed following the criteria defined in Circulation 2009. Results Subjects with combination of three metabolic syndrome components of triglycerides, abdominal obesity, and fasting glucose had the highest intraocular pressure. And subjects with the combination of four components of blood pressure, high-density lipoproteins, triglycerides, fasting glucose had a significantly higher intraocular pressure than ones with the combination of all five metabolic syndrome components. Conclusions The difference in the risk of high intraocular pressure according to the different combination of the metabolic syndrome components could be confirmed. If additional follow-up studies are conducted, the findings can be used as an indicator for predicting intraocular pressure increases in patients with metabolic syndrome.
机译：背景技术尽管代谢综合征与眼压之间的关系是众所周知的，但是尚未积极研究眼压与代谢综合征的成分的不同组合之间的关系。该研究旨在研究眼压与代谢综合征成分及其不同组合之间的关系。方法纳入2011年1月至2013年12月间就诊于社区医院进行健康检查的19-79岁的31,211位健康人。至少有一只眼睛有眼内疾病史的受试者和接受青光眼药物治疗的受试者被排除在外。代谢综合征是按照Circulation 2009中定义的标准诊断的。结果甘油三酸酯，腹部肥胖和空腹血糖这三种代谢综合征成分组合的受试者眼内压最高。血压，高密度脂蛋白，甘油三酸酯，空腹血糖这四种成分相结合的受试者的眼内压明显高于所有五个代谢综合征成分的组合。结论可以根据代谢综合征成分的不同组合确定高眼压风险的差异。如果进行其他随访研究，则该发现可作为预测代谢综合征患者眼内压升高的指标。

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