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首页> 外文期刊>BMC Medical Informatics and Decision Making >Development of a web-based tool for the assessment of health and economic outcomes of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA)
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Development of a web-based tool for the assessment of health and economic outcomes of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA)

机译：开发基于网络的工具，以评估“积极和健康老龄化欧洲创新伙伴关系”（AHA的EIP）的健康和经济成果

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Background The European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) is a European Commission led policy initiative to address the challenges of demographic change in Europe. For monitoring the health and economic impact of the social and technological innovations carried out by more than 500 stakeholder's groups ('commitments') participating in the EIP on AHA, a generic and flexible web-based monitoring and assessment tool is currently being developed. Aim This paper describes the approach for developing and implementing this web-based tool, its main characteristics and capability to provide specific outcomes that are of value to the developers of an intervention, as well as a series of case studies planned before wider rollout. Methods The tool builds up from a variety of surrogate endpoints commonly used across the diverse set of EIP on AHA commitments in order to estimate health and economic outcomes in terms of incremental changes in quality adjusted life years (QALYs) as well as health and social care utilisation. A highly adaptable Markov model with initially three mutually exclusive health states ('baseline health', 'deteriorated health' and 'death') provides the basis for the tool which draws from an extensive database of epidemiological, economic and effectiveness data; and also allows further customisation through remote data entry enabling more accurate and context specific estimation of intervention impact. Both probabilistic sensitivity analysis and deterministic scenario analysis allow assessing the impact of parameter uncertainty on intervention outcomes. A set of case studies, ranging from the pre-market assessment of early healthcare technologies to the retrospective analysis of established care pathways, will be carried out before public rollout, which is envisaged end 2015. Conclusion Monitoring the activities carried out within the EIP on AHA requires an approach that is both flexible and consistent in the way health and economic impact is estimated across interventions and commitments. The added value for users of the MAFEIP-tool is its ability to provide an early assessment of the likelihood that interventions in their current design will achieve the anticipated impact, and also to identify what drives interventions' effectiveness or efficiency to guide further design, development or evaluation.
机译：背景信息关于积极健康的老龄化的欧洲创新伙伴关系（EIP on AHA）是由欧盟委员会领导的一项政策计划，旨在应对欧洲人口变化的挑战。为了监视参与AHA的EIP的500多个利益相关者团体（“承诺”）进行的社会和技术创新的健康和经济影响，目前正在开发一种基于Web的通用且灵活的监视和评估工具。目的本文介绍了开发和实施此基于Web的工具的方法，其主要特征和提供对干预措施开发人员有价值的特定结果的能力，以及在广泛推广之前计划的一系列案例研究。方法该工具是基于在AHA承诺的EIP的不同集合中通常使用的各种替代端点构建的，目的是根据质量调整生命年（QALY）以及健康和社会护理方面的增量变化来估计健康和经济结果利用。具有高度适应性的马尔可夫模型，最初具有三个相互排斥的健康状态（“基线健康”，“恶化的健康”和“死亡”），为该工具提供了基础，该工具来自流行病学，经济和有效性数据的广泛数据库;并且还允许通过远程数据输入进行进一步的自定义，从而实现对干预效果的更准确和特定于上下文的估计。概率敏感性分析和确定性情景分析均允许评估参数不确定性对干预结果的影响。一系列案例研究，包括从早期医疗技术的上市前评估到已建立的医疗路径的回顾性分析，将在公众推广之前进行，预计于2015年底完成。结论监督在EIP中开展的活动AHA要求采用一种既灵活又一致的方法来估计各种干预措施和承诺对健康和经济的影响。 MAFEIP工具用户的附加价值在于它能够对当前设计中的干预措施将实现预期影响的可能性进行早期评估的能力，并能确定驱动干预措施的有效性或效率的因素，以指导进一步的设计，开发或评估。

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